Date published: 2026-5-11

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Arachidonyl acetate (CAS 56663-39-9)

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Application:
Arachidonyl acetate is an endocannabinoid that binds to the CB1 and CB2 receptor.
CAS Number:
56663-39-9
Molecular Weight:
332.52
Molecular Formula:
C22H36O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arachidonyl acetate, with the CAS number 56663-39-9, is an esterified derivative of arachidonic acid, a polyunsaturated omega-6 fatty acid that is a vital component of cell membranes and a precursor to various signaling molecules. This chemical modification involves the esterification of arachidonic acid with acetate, enhancing its lipophilic properties and altering its interaction with biological membranes. In research, arachidonyl acetate is primarily used to study lipid metabolism and the biochemical pathways of fatty acids. Its role as a mimic or analog of arachidonic acid allows scientists to investigate its incorporation into cellular lipids and the resulting effects on cellular functions. This is particularly relevant in studies focusing on the modulation of the inflammatory cascade, as arachidonic acid derivatives are critical in the synthesis of eicosanoids, which are signaling molecules that play key roles in inflammation and immune responses. Furthermore, arachidonyl acetate is employed in the synthesis of stable isotope-labeled compounds, which are crucial for tracing and studying metabolic pathways in lipid research. Its application extends to the development of experimental models in biochemistry and cell biology, where understanding lipid dynamics is essential. Through these uses, arachidonyl acetate contributes to a deeper understanding of lipid biochemistry and the complex network of cellular signaling pathways.


Arachidonyl acetate (CAS 56663-39-9) References

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  2. Inhibition of ligand binding to G protein-coupled receptors by arachidonic acid.  |  Bordayo, EZ., et al. 2005. J Mol Neurosci. 27: 185-94. PMID: 16186629
  3. Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin.  |  Alonso, MT., et al. 1990. Biochem J. 272: 435-43. PMID: 2125206
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  6. Eosinophil chemotactic factor. Release from human polymorphonuclear neutrophils by arachidonic acid.  |  Tesch, H., et al. 1979. Int Arch Allergy Appl Immunol. 58: 436-46. PMID: 35469
  7. Lipid chemotaxins isolated from culture filtrates of Escherichia coli and from oxidized lipids.  |  Sahu, S. and Lynn, WS. 1977. Inflammation. 2: 47-54. PMID: 367961
  8. Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain.  |  Chen, MX. and Cohen, PT. 1997. FEBS Lett. 400: 136-40. PMID: 9000529
  9. Bioassay apparatus for rodent olfactory preferences under laboratory and field conditions  |  Gawienowski A M, Keedy D A, Stacewicz-Sapuntzakis M. 1979. Journal of Chemical Ecology,. 5: 595-601.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arachidonyl acetate, 5 mg

sc-214552
5 mg
$15.00