AKAP 95 Antibody (22-Z): sc-100643
- AKAP 95 Antibody (22-Z) is a mouse monoclonal IgG2a κ, cited in 6 publications, provided at 100 µg/ml
- raised against recombinant AKAP 95 of human origin
- recommended for detection of AKAP 95 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for AKAP 95 Antibody (22-Z). This work is in progress.
AKAP 95 Antibody (22-Z) is a mouse monoclonal IgG2a antibody that detects AKAP 95 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). AKAP 95, also known as AKAP 8, is a crucial nuclear matrix protein predominantly expressed in vital organs such as the liver, heart, pancreas, kidney, and skeletal muscle. Primary function involves the compartmentalization of protein kinase A (PKA) signaling, which is essential for maintaining specific localization within the cell. This localization is achieved through AKAP 95 interaction with the RII regulatory subunit of PKA and specific anchoring proteins, known as A-kinase anchoring proteins (AKAPs). During mitosis, AKAP 95 is recruited to chromosomes, playing a pivotal role in mitotic progression and ensuring proper cell division. AKAP 95 forms a complex with HA95 and histone deacetylase 3 (HDAC3), which is vital for the deacetylation of Histone H3 during mitosis, highlighting its importance in regulating gene expression and chromatin dynamics. Anti-AKAP 95 antibody (22-Z) serves as an invaluable tool for researchers studying PKA signaling pathways and their implications in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AKAP 95 Antibody (22-Z) | sc-100643 | 100 µg/ml | $339.00 |