![3-[(2-Bromo-4-chlorophenoxy)methyl]-4-methoxybenzaldehyde - chemical structure image](https://media.scbt.com/product/3--2-bromo-4-chlorophenoxy-methyl-4-methoxybenzaldehyde-structure_22_67_b_226744.jpg)
![3-[(2-Bromo-4-chlorophenoxy)methyl]-4-methoxybenzaldehyde - chemical structure image](https://media.scbt.com/product/3--2-bromo-4-chlorophenoxy-methyl-4-methoxybenzaldehyde-structure_22_67_t_226744.jpg "Molecular structure of 3-[(2-Bromo-4-chlorophenoxy)methyl]-4-methoxybenzaldehyde")
3-[(2-Bromo-4-chlorophenoxy)methyl]-4-methoxybenzaldehyde
QUICK LINKS
DAPH-7 is a highly selective procarcinogenic protein kinase C-betaII (PKCbetaII) inhibitor that can also inhibit nPKCs and aPKCs, and upregulate VCAM-1, in a dose dependent manner. The compound may act to inhibit a variety of kinases, such as, protein kinase A, casein kinase I and II, c-src kinase, c-lyn kinase, c-fgr kinase, and v-abl kinase at an IC50 of greater than 50 muM. Studies show that inhibitory DAPHs can reconstruct Sup35 prion-specific intermolecular interfaces to create morphologically altered aggregates with diminished infectivity and self-templating activity. When DAPHs alter the folding of Sup35s amyloidogenic core it blocks amyloidogenic oligomerization and specific recognition events that nucleate prion assembly. Research shows that DAPH-7, also known as, CGP-53353, can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(2-Bromo-4-chlorophenoxy)methyl]-4-methoxybenzaldehyde, 500 mg | sc-310421 | 500 mg | $135.00 |