Date published: 2025-10-4

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Psoromic acid (CAS 7299-11-8)

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Alternate Names:
Parellic acid
Application:
Psoromic acid is a benzodioxepine compound for proteomics research
CAS Number:
7299-11-8
Molecular Weight:
358.31
Molecular Formula:
C18H14O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Psoromic acid is an organic compound of interest in the field of lichenology and natural products chemistry. As a secondary metabolite found in certain lichens, it serves as a subject for studying the chemical ecology and symbiotic relationships within lichen communities. Researchers investigate psoromic acid for its role in lichen defense mechanisms against microbial attack and herbivory, as well as its contribution to the lichens′ ability to endure extreme environmental conditions. In the area of environmental monitoring, this compound is analyzed for its potential as a bioindicator of air quality, as lichens are known to absorb and accumulate substances from the atmosphere. Additionally, psoromic acid′s unique chemical structure is explored in the synthesis of new organic compounds, where it may function as a building block or lead compound due to its specific functional groups. Its presence also aids in chemotaxonomy, helping to classify lichens based on their chemical profiles.


Psoromic acid (CAS 7299-11-8) References

  1. Cytotoxic and apoptotic effects on hepatocytes of secondary metabolites obtained from lichens.  |  Correché, ER., et al. 2004. Altern Lab Anim. 32: 605-15. PMID: 15757498
  2. Parallel evolution and phenotypic divergence in lichenized fungi: a case study in the lichen-forming fungal family Graphidaceae (Ascomycota: Lecanoromycetes: Ostropales).  |  Rivas Plata, E. and Lumbsch, HT. 2011. Mol Phylogenet Evol. 61: 45-63. PMID: 21605691
  3. Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.  |  Samatov, TR., et al. 2012. Chembiochem. 13: 640-4. PMID: 22334518
  4. Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.  |  Deraeve, C., et al. 2012. J Am Chem Soc. 134: 7384-91. PMID: 22480322
  5. Antioxidative and cardiovascular-protective activities of metabolite usnic acid and psoromic acid produced by lichen species Usnea complanata under submerged fermentation.  |  Behera, BC., et al. 2012. Pharm Biol. 50: 968-79. PMID: 22775414
  6. Cytotoxic evaluation of phenolic compounds from lichens against melanoma cells.  |  Brandão, LF., et al. 2013. Chem Pharm Bull (Tokyo). 61: 176-83. PMID: 23207680
  7. Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.  |  Lauinger, IL., et al. 2013. J Nat Prod. 76: 1064-70. PMID: 23806111
  8. In vitro antitumor activities of the lichen compounds olivetoric, physodic and psoromic acid in rat neuron and glioblastoma cells.  |  Emsen, B., et al. 2016. Pharm Biol. 54: 1748-62. PMID: 26704132
  9. Antibacterial activities of natural lichen compounds against Streptococcus gordonii and Porphyromonas gingivalis.  |  Sweidan, A., et al. 2017. Fitoterapia. 121: 164-169. PMID: 28736072
  10. Inhibition of the Amyloidogenesis of Transthyretin by Natural Products and Synthetic Compounds.  |  Yokoyama, T. and Mizuguchi, M. 2018. Biol Pharm Bull. 41: 979-984. PMID: 29962408
  11. Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes.  |  Gulçin, İ., et al. 2018. Int J Biol Macromol. 119: 741-746. PMID: 30076927
  12. Antimycobacterial, Enzyme Inhibition, and Molecular Interaction Studies of Psoromic Acid in Mycobacterium tuberculosis: Efficacy and Safety Investigations.  |  Hassan, STS., et al. 2018. J Clin Med. 7: PMID: 30127304
  13. Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties.  |  Hassan, STS., et al. 2019. Molecules. 24: PMID: 31405197
  14. Antimelanoma Potential of Cladonia mitis Acetone Extracts - Comparative in Vitro Studies in Relation to Usnic Acid Content.  |  Grudzińska, M., et al. 2022. Chem Biodivers. 19: e202200408. PMID: 35652525

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Psoromic acid, 2.5 mg

sc-363581
2.5 mg
$1030.00

Psoromic acid, 10 mg

sc-363581A
10 mg
$2050.00