Date published: 2025-11-20

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8-Hydroxy-7-methoxycoumarin (CAS 19492-03-6)

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CAS Number:
19492-03-6
Molecular Weight:
192.17
Molecular Formula:
C10H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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8-Hydroxy-7-methoxycoumarin (8-HMC) is a naturally occurring derivative of coumarin. 8-Hydroxy-7-methoxycoumarin is found abundantly in plants and extensively investigated in scientific research. Although the precise mechanism of action of 8-Hydroxy-7-methoxycoumarin remains elusive, it is believed to engage in multiple pathways. It is thought to interact with various receptors, enzymes, and proteins, influencing their activity and function.


8-Hydroxy-7-methoxycoumarin (CAS 19492-03-6) References

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  2. Using the scoparone O-demethylase assay for categorizing types of hepatic microsomal monooxygenase inducers.  |  Kato, S. and Yamamoto, K. 1989. Bull Environ Contam Toxicol. 42: 489-94. PMID: 2496779
  3. Progress in the Chemistry of Naturally Occurring Coumarins.  |  Sarker, SD. and Nahar, L. 2017. Prog Chem Org Nat Prod. 106: 241-304. PMID: 28762091
  4. Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review.  |  Li, AL., et al. 2018. J Ethnopharmacol. 210: 260-274. PMID: 28838654
  5. 5-Phenylcoumarin Derivatives: Design, Synthesis, and Vasodilatory Activity.  |  Wang, C., et al. 2018. Chem Biodivers. 15: e1800255. PMID: 30194801
  6. Efficient degradation of Orange G with persulfate activated by recyclable FeMoO4.  |  Lin, X., et al. 2019. Chemosphere. 214: 642-650. PMID: 30292046
  7. Daphne giraldii Nitsche (Thymelaeaceae): Phytochemistry, pharmacology and medicinal uses.  |  Han, S., et al. 2020. Phytochemistry. 171: 112231. PMID: 31901473
  8. The genus Daphne: A review of its traditional uses, phytochemistry and pharmacology.  |  Moshiashvili, G., et al. 2020. Fitoterapia. 143: 104540. PMID: 32165275
  9. Comparative Metabolomics Profiling Reveals Key Metabolites and Associated Pathways Regulating Tuber Dormancy in White Yam (Dioscorea rotundata Poir.).  |  Nwogha, JS., et al. 2023. Metabolites. 13: PMID: 37233651
  10. Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines.  |  Kolodziej, H., et al. 1997. Z Naturforsch C J Biosci. 52: 240-4. PMID: 9167275

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

8-Hydroxy-7-methoxycoumarin, 25 mg

sc-268447
25 mg
$129.00