Date published: 2025-10-14

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D-Pinitol (CAS 10284-63-6)

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Alternate Names:
3-O-Methyl-D-chiro-inositol
Application:
D-Pinitol is a biological precursor for isosteres of inositiol
CAS Number:
10284-63-6
Purity:
≥98%
Molecular Weight:
194.18
Molecular Formula:
C7H14O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Pinitol, a naturally occurring compound found primarily in legumes and certain other plants, is a cyclitol, a type of sugar alcohol that mimics the structure of inositol. This biomolecule has garnered attention in the fields of plant physiology and environmental biology, where it is studied for its role in stress response, particularly in osmoregulation and drought tolerance. D-Pinitol functions by acting as an osmoprotectant, helping plants to cope with abiotic stress by stabilizing the intracellular environment against the detrimental effects of dehydration. Research into D-Pinitol has revealed its capability to accumulate in plant cells under stress conditions, contributing to the maintenance of cell turgor and protection of cellular structures against damage caused by water deficiency. Further, D-Pinitol is involved in the modulation of various signaling pathways that mediate plant responses to environmental stimuli. Its role extends to biochemical studies where it is used as a tool to investigate the transport and metabolism of sugar alcohols within plant systems, offering insights into the metabolic adaptations plants employ to survive adverse conditions. This research not only enhances understanding of plant biology but also aids in developing strategies for improving crop resilience to stress.


D-Pinitol (CAS 10284-63-6) References

  1. Salt Stress Perception and Plant Growth Regulators in the Halophyte Mesembryanthemum crystallinum.  |  Thomas, JC. and Bohnert, HJ. 1993. Plant Physiol. 103: 1299-1304. PMID: 12232022
  2. D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis.  |  Liu, X. and Koyama, T. 2023. Molecules. 28: PMID: 37175278
  3. Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance.  |  Medina-Vera, D., et al. 2024. Neural Regen Res. 19: 289-295. PMID: 37488880
  4. D-Pinitol Content and Antioxidant and Antidiabetic Activities of Five Bougainvillea spectabilis Willd. Cultivars.  |  Abo-Elghiet, F., et al. 2023. Pharmaceuticals (Basel). 16: PMID: 37513920
  5. Effect of D-pinitol on MK-801-induced schizophrenia-like behaviors in mice.  |  Kim, JY., et al. 2023. Phytother Res. 37: 5904-5915. PMID: 37654104
  6. D-Pinitol attenuates postmenopausal symptoms in ovariectomized mice.  |  Kang, WC., et al. 2023. Life Sci. 333: 122147. PMID: 37802198
  7. Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice.  |  Li, X., et al. 2023. Front Mol Neurosci. 16: 1251513. PMID: 38025258
  8. D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.  |  Li, X., et al. 2024. Phytother Res. 38: 1681-1694. PMID: 38311336
  9. D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice.  |  Khan, A., et al. 2024. Iran J Basic Med Sci. 27: 326-334. PMID: 38333757
  10. D-Pinitol mitigates post-traumatic stress disorder-like behaviors induced by single prolonged stress in mice through mineralocorticoid receptor antagonism.  |  Kong, CH., et al. 2024. Prog Neuropsychopharmacol Biol Psychiatry. 132: 110990. PMID: 38467326
  11. The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.  |  Zhao, W., et al. 2024. J Cachexia Sarcopenia Muscle. 15: 934-948. PMID: 38553831
  12. Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme: in vivo and in silico studies.  |  Haque, MF., et al. 2024. Front Chem. 12: 1366844. PMID: 38690012
  13. d-Pinitol Improves Diabetic Sarcopenia by Regulation of the Gut Microbiome, Metabolome, and Proteome in STZ-Induced SAMP8 Mice.  |  Yu, X., et al. 2024. J Agric Food Chem. 72: 14466-14478. PMID: 38875577

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Pinitol, 100 mg

sc-257293
100 mg
$23.00