Date published: 2025-10-18

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2-Naphthoxyacetic acid (CAS 120-23-0)

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Alternate Names:
BNOA
CAS Number:
120-23-0
Molecular Weight:
202.21
Molecular Formula:
C12H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Naphthoxyacetic acid (2-NOA) is an organic compound classified as a naphthoic acid and characterized by its colorless solid form. 2-Naphthoxyacetic acid displays solubility in water. This natural product can be found in various plants, including certain Nicotiana species, as well as in certain fungi. In scientific research, 2-Naphthoxyacetic acid serves as a tool for investigating the effects of auxins on plant development. It acts as a potent inhibitor of auxin-dependent plant growth, enabling the exploration of auxins′ impact on various aspects of plant growth and development. Additionally, by acting as an auxin antagonist, 2-Naphthoxyacetic acid binds to the auxin receptor, thereby impeding the binding of auxin to the receptor. Consequently, this inhibition disrupts the downstream signaling pathway of auxin, leading to the suppression of auxin-mediated plant growth and development.


2-Naphthoxyacetic acid (CAS 120-23-0) References

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  2. 2-Amino-2-thiazoline and its 1:1 organic salt with 2-naphthoxyacetic acid.  |  Lynch, DE. 2004. Acta Crystallogr C. 60: o677-9. PMID: 15345854
  3. Primary Action of Indole-3-acetic Acid in Crown Gall Tumors: Increase of Solute Uptake.  |  Rausch, T., et al. 1984. Plant Physiol. 75: 354-8. PMID: 16663625
  4. Auxin influx inhibitors 1-NOA, 2-NOA, and CHPAA interfere with membrane dynamics in tobacco cells.  |  Lanková, M., et al. 2010. J Exp Bot. 61: 3589-98. PMID: 20595238
  5. Simultaneous determination of 13 phytohormones in oilseed rape tissues by liquid chromatography-electrospray tandem mass spectrometry and the evaluation of the matrix effect.  |  Fan, S., et al. 2011. J Sep Sci. 34: 640-50. PMID: 21312330
  6. Simultaneous determination of plant growth regulators 1-naphthylacetic acid and 2-naphthoxyacetic acid in fruit and vegetable samples by room temperature phosphorescence.  |  Murillo Pulgarín, JA., et al. 2012. Phytochem Anal. 23: 214-21. PMID: 21805518
  7. Simultaneous determination of 2-naphthoxyacetic acid and indole-3-acetic acid by first derivation synchronous fluorescence spectroscopy.  |  Liu, X. and Wan, Y. 2013. Spectrochim Acta A Mol Biomol Spectrosc. 111: 230-6. PMID: 23651742
  8. Determination of plant growth regulators in pears by microwave-assisted extraction and liquid chromatography with electrospray ionization mass spectrometry.  |  Mao, X., et al. 2014. J Sep Sci. 37: 1352-8. PMID: 24659386
  9. Inhibition of auxin transport and auxin signaling and treatment with far red light induces root coiling in the phospholipase-A mutant ppla-I-1. Significance for surface penetration?  |  Perrineau, F., et al. 2016. J Plant Physiol. 196-197: 53-9. PMID: 27058428
  10. Self-Assembled and Cross-Linked Animal and Plant-Based Polysaccharides: Chitosan-Cellulose Composites and Their Anion Uptake Properties.  |  Udoetok, IA., et al. 2016. ACS Appl Mater Interfaces. 8: 33197-33209. PMID: 27802018
  11. Phytohormone Behavior in the Model Environment of Plant and Human Lipid Membranes.  |  Flasiński, M. and Święchowicz, P. 2017. J Phys Chem B. 121: 6175-6183. PMID: 28582619
  12. Modified QuEChERS method for 24 plant growth regulators in grapes using LC-MS/MS.  |  Pu, CH., et al. 2018. J Food Drug Anal. 26: 637-648. PMID: 29567233
  13. Small molecules restore the function of mutant CLC5 associated with Dent disease.  |  Liu, J., et al. 2021. J Cell Mol Med. 25: 1319-1322. PMID: 33200471

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Naphthoxyacetic acid, 100 g

sc-254284
100 g
$46.00

2-Naphthoxyacetic acid, 500 g

sc-254284A
500 g
$209.00