Date published: 2026-1-21

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1,2-Pentanediol (CAS 5343-92-0)

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CAS Number:
5343-92-0
Purity:
96%
Molecular Weight:
104.15
Molecular Formula:
C5H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Pentanediol is an organic compound known to be a component of many commercial products, including cosmetics, detergents, and lubricants. It is used in a variety of applications, including as a solvent, a plasticizer, a surfactant, and a reactant in the synthesis of other compounds. 1,2-Pentanediol is used as a solvent in chemical reactions, as it is miscible with both water and organic solvents. It is also used as a plasticizer in the manufacture of polymers, as it can reduce the glass transition temperature of the polymer. Additionally, it is used as a reactant in the synthesis of other compounds, such as polyols and polyurethanes.


1,2-Pentanediol (CAS 5343-92-0) References

  1. Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol.  |  Yamada-Onodera, K., et al. 2006. J Biosci Bioeng. 102: 545-51. PMID: 17270720
  2. The influence of alcohol, propylene glycol and 1,2-pentanediol on the permeability of hydrophilic model drug through excised pig skin.  |  Duracher, L., et al. 2009. Int J Pharm. 374: 39-45. PMID: 19446757
  3. Effect of hydrocarbon chain length in 1,2-alkanediols on percutaneous absorption of metronidazole: toward development of a general vehicle for controlled release.  |  Li, N., et al. 2014. AAPS PharmSciTech. 15: 354-63. PMID: 24395400
  4. Directing enzyme devolution for biosynthesis of alkanols and 1,n-alkanediols from natural polyhydroxy compounds.  |  Dai, L., et al. 2017. Metab Eng. 44: 70-80. PMID: 28928052
  5. Single-Step Hydrogenolysis of Furfural to 1,2-Pentanediol Using a Bifunctional Rh/OMS-2 Catalyst.  |  Pisal, DS. and Yadav, GD. 2019. ACS Omega. 4: 1201-1214. PMID: 31459394
  6. Tuning the Molecular and Cationic Affinity in a Series of Multifunctional Metal-Organic Frameworks Based on Dodecanuclear Zn(II) Carboxylate Wheels.  |  Lysova, AA., et al. 2019. J Am Chem Soc. 141: 17260-17269. PMID: 31584810
  7. Topical delivery of niacinamide: Influence of neat solvents.  |  Iliopoulos, F., et al. 2020. Int J Pharm. 579: 119137. PMID: 32057889
  8. Insights on the Extraction Performance of Alkanediols and Glycerol: Using Juglans regia L. Leaves as a Source of Bioactive Compounds.  |  Vieira, V., et al. 2020. Molecules. 25: PMID: 32471297
  9. Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream.  |  Sigg, M. and Daniels, R. 2020. Pharmaceutics. 12: PMID: 33233527
  10. Hydrogenolysis of Furfuryl Alcohol to 1,2-Pentanediol Over Supported Ruthenium Catalysts.  |  Yamaguchi, A., et al. 2021. ChemistryOpen. 10: 731-736. PMID: 34109757
  11. The effect of alkanediols on the release of triamcinolone acetonide from semisolid dosage forms.  |  Sigg, M. and Daniels, R. 2021. Int J Pharm. 605: 120843. PMID: 34216765
  12. Impact of Alkanediols on Stratum Corneum Lipids and Triamcinolone Acetonide Skin Penetration.  |  Sigg, M. and Daniels, R. 2021. Pharmaceutics. 13: PMID: 34575527
  13. In Situ Ruthenium Catalyst Modification for the Conversion of Furfural to 1,2-Pentanediol.  |  Bruna, L., et al. 2022. Nanomaterials (Basel). 12: PMID: 35159673

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Pentanediol, 50 ml

sc-222855
50 ml
$84.00

1,2-Pentanediol, 250 ml

sc-222855A
250 ml
$290.00