Molecular structure of L-(−)-Glucose, CAS Number: 921-60-8
L-(−)-Glucose (CAS 921-60-8)
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Alternate Names:
L-Glucose
Application:
L-(−)-Glucose is an enantiomer of the more common D-glucose
CAS Number:
921-60-8
Purity:
≥97%
Molecular Weight:
180.16
Molecular Formula:
C6H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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L-(−)-Glucose, an enantiomer of the ubiquitous D-glucose, plays a fascinating role in the study of carbohydrate metabolism and enzymatic specificity. Unlike its counterpart, L-(−)-Glucose cannot be utilized by cells as an energy source, a distinctive characteristic attributed to its inability to be phosphorylated by hexokinase, the enzyme responsible for the initial step in the glycolytic pathway. This specificity stems from the stereochemical configuration of L-(−)-Glucose, which is a mirror image of D-glucose, affecting its interaction with the active site of hexokinase.
L-(−)-Glucose (CAS 921-60-8) References
- Vagotomy attenuates effects of L-glucose but not of D-glucose on spontaneous alternation performance. | Talley, CP., et al. 2002. Physiol Behav. 77: 243-9. PMID: 12419400
- L-glucose absorption in house sparrows (Passer domesticus) is nonmediated. | Chang, MH., et al. 2004. J Comp Physiol B. 174: 181-8. PMID: 14676966
- A novel bioconversion of L-fructose to L-glucose by Klebsiella pneumoniae. | Leang, K., et al. 2003. J Biosci Bioeng. 95: 310-2. PMID: 16233412
- An L-glucose catabolic pathway in Paracoccus species 43P. | Shimizu, T., et al. 2012. J Biol Chem. 287: 40448-56. PMID: 23038265
- Short and sweet: (D)-glucose to (L)-glucose and (L)-glucuronic acid. | Martínez, RF., et al. 2014. Angew Chem Int Ed Engl. 53: 1160-2. PMID: 24310928
- Uptake of a fluorescent L-glucose derivative 2-NBDLG into three-dimensionally accumulating insulinoma cells in a phloretin-sensitive manner. | Sasaki, A., et al. 2016. Hum Cell. 29: 37-45. PMID: 26553070
- Chronic Sucralose or L-Glucose Ingestion Does Not Suppress Food Intake. | Wang, QP., et al. 2017. Cell Metab. 26: 279-280. PMID: 28768164
- Structural basis of L-glucose oxidation by scyllo-inositol dehydrogenase: Implications for a novel enzyme subfamily classification. | Fukano, K., et al. 2018. PLoS One. 13: e0198010. PMID: 29799855
- The Glucose Sensitivity of Insulin Secretion-Lessons from In Vivo and In Vitro Studies in Mice. | Ahrén, B. 2022. Biomolecules. 12: PMID: 35883532
- Discovery of α-l-Glucosidase Raises the Possibility of α-l-Glucosides in Nature. | Shishiuchi, R., et al. 2022. ACS Omega. 7: 47411-47423. PMID: 36570207
- Active transport of L-glucose by isolated small intestine of the dietary-restricted rat. | Neale, RJ. and Wiseman, G. 1968. J Physiol. 198: 601-11. PMID: 5685290
Inhibitor of:
CYP4A30B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-(−)-Glucose, 250 mg | sc-221793 | 250 mg | $37.00 | |||
L-(−)-Glucose, 500 mg | sc-221793A | 500 mg | $61.00 |