Molecular structure of Brassicasterol, CAS Number: 474-67-9
Brassicasterol (CAS 474-67-9)
See product citations (3)
Alternate Names:
5,22-Cholestadien-24β-methyl-3β-ol
Application:
Brassicasterol is inhibit sterol Δ24-reductase
CAS Number:
474-67-9
Purity:
≥95%
Molecular Weight:
398.66
Molecular Formula:
C28H46O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Brassicasterol is found in a variety of marine organisms and in members of the Brassicaceae family of plants. In ecological and environmental studies, Brassicasterol is employed as a biomarker for the presence of certain algae and phytoplankton, aiding researchers in understanding food web dynamics and the flow of organic carbon in marine systems. Its relative abundance in sediments and water columns can also provide valuable information on paleoceanographic conditions and climate change impacts over time. Additionally, Brassicasterol is utilized in the field of lipidomics to explore the complex lipid profiles of organisms, contributing to a deeper understanding of cellular lipid metabolism.
Brassicasterol (CAS 474-67-9) References
- Mass spectrometry characterization of the 5alpha-, 7alpha-, and 7beta-hydroxy derivatives of beta-sitosterol, campesterol, stigmasterol, and brassicasterol. | Bortolomeazzi, R., et al. 1999. J Agric Food Chem. 47: 3069-74. PMID: 10552610
- The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease. | Vanmierlo, T., et al. 2011. Acta Psychiatr Scand. 124: 184-92. PMID: 21585343
- A comparative calorimetric study of the effects of cholesterol and the plant sterols campesterol and brassicasterol on the thermotropic phase behavior of dipalmitoylphosphatidylcholine bilayer membranes. | Benesch, MG. and McElhaney, RN. 2014. Biochim Biophys Acta. 1838: 1941-9. PMID: 24704414
- Identification of 27-nor-(24R)-24-methylcholesta-5,22-dien-3β-ol and brassicasterol as the major sterols of the marine dinoflagellateGymnodinium simplex. | Goad, LJ. and Withers, N. 1982. Lipids. 17: 853-8. PMID: 27519432
- Isolation of brassicasterol from steam deodorizer distillate of rapeseed oil: Some properties of its acetate tetrabromide and its reduction to 22,23-dihydrobrassicasterol. | Hircher, HW. and Rosenstein, FU. 1973. Lipids. 8: 453-8. PMID: 27520029
- Sterols in Infant Formulas: A Bioaccessibility Study. | Hamdan, IJA., et al. 2018. J Agric Food Chem. 66: 1377-1385. PMID: 29369630
- Fucosterol Causes Small Changes in Lipid Storage and Brassicasterol Affects some Markers of Lipid Metabolism in Atlantic Salmon Hepatocytes. | Liland, NS., et al. 2018. Lipids. 53: 737-747. PMID: 30259993
- Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments. | Hassan, STS. 2020. Biomedicines. 8: PMID: 32456343
- Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol. | Yazawa, Y., et al. 2020. J Nat Med. 74: 680-688. PMID: 32488609
- Advances in various techniques for isolation and purification of sterols. | Dikshit, S., et al. 2020. J Food Sci Technol. 57: 2393-2403. PMID: 32549589
- Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer. | Xu, Y., et al. 2020. Biomedicines. 8: PMID: 32972001
- Phytophthora capsici sterol reductase PcDHCR7 has a role in mycelium development and pathogenicity. | Wang, W., et al. 2022. Open Biol. 12: 210282. PMID: 35382565
- Triacylglycerides and Cholesterol in Organic Milk from Chiapas, Mexico. | González, JJP., et al. 2022. Animals (Basel). 12: PMID: 35625137
- Brassicasterol inhibits hepatitis B virus-associated hepatocellular carcinoma development via suppression of AKT signaling pathway. | Zeng, J., et al. 2023. Infect Agent Cancer. 18: 22. PMID: 37081537
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brassicasterol, 5 mg | sc-214621 | 5 mg | $457.00 |