Date published: 2025-10-16

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γ-Cyclodextrin (CAS 17465-86-0)

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Alternate Names:
Cyclomaltooctaose, Cyclooctaamylose, Schardinger γ-Dextrin, gamma-Cyclodextrin
Application:
γ-Cyclodextrin is a cyclic oligosaccharide
CAS Number:
17465-86-0
Molecular Weight:
1297.12
Molecular Formula:
C48H80O40
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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γ-Cyclodextrin is one of the three common forms of Cyclodextrin. The compound is composed of eight glucose units and forms the shape of a hollow truncated cone with a hydrophylic exterior and hydrophobic interior. Due to the larger number of glucose units the compound is more favored than the alpha (sc-257031) and beta (sc-204430) counterparts and can form inclusion bodies with steroids and macrocycles. Due to γ-Cyclodextrin flexibility and non-coplanar structure the compound has a solubility of 232 g/L, 25degC. The compound can also be digested with both salivary and pancreatic amylase unlike alpha- and beta-Cyclodextrin.


γ-Cyclodextrin (CAS 17465-86-0) References

  1. Introduction and General Overview of Cyclodextrin Chemistry.  |  Szejtli, J. 1998. Chem Rev. 98: 1743-1754. PMID: 11848947
  2. gamma-Cyclodextrin: a review on enzymatic production and applications.  |  Li, Z., et al. 2007. Appl Microbiol Biotechnol. 77: 245-55. PMID: 17891389
  3. Cyclodextrins for drug delivery.  |  Laza-Knoerr, AL., et al. 2010. J Drug Target. 18: 645-56. PMID: 20497090
  4. In vitro action of human and porcine alpha-amylases on cyclomalto-oligosaccharides.  |  Kondo, H., et al. 1990. Carbohydr Res. 204: 207-13. PMID: 2279246
  5. Titanocene / cyclodextrin supramolecular systems: a theoretical approach.  |  Riviş, A., et al. 2012. Chem Cent J. 6: 129. PMID: 23122334
  6. γ-Cyclodextrin cuprate sandwich-type complexes.  |  Bagabas, AA., et al. 2013. Inorg Chem. 52: 2854-61. PMID: 23432138
  7. γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water.  |  Floresta, G., et al. 2017. J Org Chem. 82: 4631-4639. PMID: 28406307
  8. Application of cyclodextrinase in non-complexant production of γ-cyclodextrin.  |  Ji, H., et al. 2020. Biotechnol Prog. 36: e2930. PMID: 31622540
  9. Cyclodextrin Porous Liquid Materials for Efficient Chiral Recognition and Separation of Nucleosides.  |  Wang, Y., et al. 2020. ACS Appl Mater Interfaces. 12: 45916-45928. PMID: 33021090
  10. Fe(OTf)3- and γ-Cyclodextrin-Catalyzed Hydroamination of Alkenes with Carbazoles.  |  Xiao, EK., et al. 2021. Org Lett. 23: 449-453. PMID: 33356323
  11. Preparation and Spectroscopic Characterization of Inclusion Complexes of 3D Ball-Milled Rifampicin with β-cyclodextrin and γ-cyclodextrin : 3D Ball-Milled Rifampicin with β-cyclodextrin and γ-cyclodextrin.  |  Inoue, Y., et al. 2022. AAPS PharmSciTech. 23: 138. PMID: 35534746
  12. γ-Cyclodextrin-based [2]rotaxane stoppered with gold(I)-ethynyl complexation: phosphorescent sensing for nitroaromatics.  |  Yu, X., et al. 2022. Chem Commun (Camb). 58: 6284-6287. PMID: 35550657
  13. Tilmicosin/γ-Cyclodextrin complexation through supercritical carbon dioxide assistance and its pharmacokinetic and antibacterial study.  |  Ding, Y., et al. 2022. Eur J Pharm Biopharm. 181: 104-112. PMID: 36375723

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

γ-Cyclodextrin, 5 g

sc-208516
5 g
$108.00

γ-Cyclodextrin, 25 g

sc-208516A
25 g
$252.00

γ-Cyclodextrin, 100 g

sc-208516B
100 g
$837.00