Molecular structure of Deoxynivalenol, CAS Number: 51481-10-8
Deoxynivalenol (CAS 51481-10-8)
See product citations (9)
Alternate Names:
Deoxynivalenol is also known as Vomitoxin.
Application:
Deoxynivalenol is Deoxynivalenol is a Fusarium mycotoxin, known for immunosuppressive characteristics and gene deregulation.
CAS Number:
51481-10-8
Purity:
≥98%
Molecular Weight:
296.31
Molecular Formula:
C15H20O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Deoxynivalenol is a mycotoxin usually produced by Fusarium species. Often detected in grains, it can be found in wheat, barley, oats, maize, rye, and other cereal crops. Deoxynivalenol demonstrates immunosuppressive characteristics at high concentrations and immunostimulatory effects at low concentrations. Other effects of Deoxynivalenol include down-regulation of genes involved in protein synthesis, proliferation, ribosomal proteins, and mitochondria. Further studies show that Deoxynivalenol is an inducer of calcium release from the endoplasmic reticulum.
Deoxynivalenol (CAS 51481-10-8) References
- Effects of feeding grains naturally contaminated with Fusarium mycotoxins with and without a polymeric glucomannan mycotoxin adsorbent on reproductive performance and serum chemistry of pregnant gilts. | Díaz-Llano, G. and Smith, TK. 2006. J Anim Sci. 84: 2361-6. PMID: 16908638
- The effects of deoxynivalenol on gene expression in the murine thymus. | van Kol, SW., et al. 2011. Toxicol Appl Pharmacol. 250: 299-311. PMID: 21074547
- RNA Interference (RNAi) as a Potential Tool for Control of Mycotoxin Contamination in Crop Plants: Concepts and Considerations. | Majumdar, R., et al. 2017. Front Plant Sci. 8: 200. PMID: 28261252
- Do Plant-Bound Masked Mycotoxins Contribute to Toxicity? | Gratz, SW. 2017. Toxins (Basel). 9: PMID: 28264486
- Mechanism of deoxynivalenol effects on the reproductive system and fetus malformation: Current status and future challenges. | Yu, M., et al. 2017. Toxicol In Vitro. 41: 150-158. PMID: 28286114
- Impact of two mycotoxins deoxynivalenol and fumonisin on pig intestinal health. | Pierron, A., et al. 2016. Porcine Health Manag. 2: 21. PMID: 28405447
- Transcriptomics of cereal-Fusarium graminearum interactions: what we have learned so far. | Kazan, K. and Gardiner, DM. 2018. Mol Plant Pathol. 19: 764-778. PMID: 28411402
- Review of mechanisms of deoxynivalenol-induced anorexia: The role of gut microbiota. | Peng, Z., et al. 2017. J Appl Toxicol. 37: 1021-1029. PMID: 28466983
- Impact of mycotoxins on the intestine: are mucus and microbiota new targets? | Robert, H., et al. 2017. J Toxicol Environ Health B Crit Rev. 20: 249-275. PMID: 28636450
- Studies on the Presence of Mycotoxins in Biological Samples: An Overview. | Escrivá, L., et al. 2017. Toxins (Basel). 9: PMID: 28820481
- RNAi as an emerging approach to control Fusarium head blight disease and mycotoxin contamination in cereals. | Machado, AK., et al. 2018. Pest Manag Sci. 74: 790-799. PMID: 28967180
- Microbial Inhibition of Fusarium Pathogens and Biological Modification of Trichothecenes in Cereal Grains. | Wachowska, U., et al. 2017. Toxins (Basel). 9: PMID: 29261142
- The importance of accounting for sex in the search of proteomic signatures of mycotoxin exposure. | Soler, L. and Oswald, IP. 2018. J Proteomics. 178: 114-122. PMID: 29288091
- Updated Overview of Infrared Spectroscopy Methods for Detecting Mycotoxins on Cereals (Corn, Wheat, and Barley). | Levasseur-Garcia, C. 2018. Toxins (Basel). 10: PMID: 29320435
- Simultaneous detection of several Fusarium mycotoxins in cereals, grains, and foodstuffs. | Kamimura, H., et al. 1981. J Assoc Off Anal Chem. 64: 1067-73. PMID: 7287603
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Deoxynivalenol, 500 µg | sc-204711B | 500 µg | $65.00 | |||
Deoxynivalenol, 1 mg | sc-204711 | 1 mg | $99.00 | |||
Deoxynivalenol, 5 mg | sc-204711A | 5 mg | $280.00 |