ZMYM3 Inhibitors
ZMYM3 inhibitors belong to a distinct chemical class characterized by their ability to selectively target and modulate the activity of the Zinc Finger MYM-type 3 (ZMYM3) protein. ZMYM3, also known as PRAME (preferentially expressed antigen in melanoma), is a member of the MYM family of proteins and is implicated in various cellular processes, including gene regulation and transcriptional control. The inhibitors designed for ZMYM3 specifically aim to interfere with the normal function of this protein, which is often associated with transcriptional repression and chromatin organization. Researchers have focused on developing molecules that can selectively bind to ZMYM3, inhibiting its activity and thereby influencing downstream cellular processes.
ZMYM3 inhibitors is intricately crafted to interact with specific regions of the ZMYM3 protein, disrupting its normal interactions with DNA and other cellular components. Through these targeted interactions, ZMYM3 inhibitors have the potential to modulate gene expression patterns and influence cellular functions associated with ZMYM3 activity. The development of ZMYM3 inhibitors represents a promising avenue for researchers exploring the intricate mechanisms of gene regulation and chromatin dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can modulate chromatin structure by inhibiting DNA methyltransferases, potentially altering the transcriptional activity where ZMYM3 is involved. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram can inhibit zinc finger proteins by chelating zinc ions, potentially altering the structural integrity of ZMYM3. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can affect transcriptional regulation, possibly influencing the activity of ZMYM3. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108, another DNA methyltransferase inhibitor, can change gene expression profiles, possibly affecting ZMYM3's role in transcription. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
As a methyl donor, it can influence methylation patterns, potentially impacting ZMYM3's regulatory functions. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine can intercalate into DNA, possibly altering DNA accessibility for ZMYM3. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin binds to G-C rich DNA sequences, potentially competing with ZMYM3 for DNA binding. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide can inhibit transcription factors and may affect the regulatory roles of ZMYM3 indirectly. | ||||||
Ciclopirox | 29342-05-0 | sc-217893 | 25 mg | $207.00 | 2 | |
Ciclopirox can chelate metal ions, which may disrupt the metal-dependent domains of ZMYM3. | ||||||