The chemical class of WDR34 activators comprises compounds that modulate cellular energy metabolism and signaling pathways involved in the regulation of WDR34 activity. These activators primarily target AMP-activated protein kinase (AMPK), a central metabolic sensor that plays a crucial role in cellular energy homeostasis. AMPK activation occurs in response to various stimuli such as changes in cellular AMP:ATP ratios, oxidative stress, and nutrient availability.
Rapamycin, for example, indirectly activates WDR34 by inhibiting mTORC1, thereby relieving suppression via the mTOR pathway. Similarly, compounds like berberine, A769662, and AICAR directly activate AMPK, which can modulate cellular processes involving WDR34. Additionally, salicylate, resveratrol, and other AMPK activators influence WDR34 activity by regulating cellular metabolism and energy balance. These activators can impact WDR34-mediated processes through their effects on AMPK signaling, highlighting the intricate interplay between cellular metabolism and protein function. Overall, WDR34 activators represent a diverse array of compounds that target key metabolic pathways to regulate cellular processes involving WDR34.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTORC1, which may indirectly activate WDR34 by relieving its suppression via the mTOR pathway. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates AMPK, which can modulate cellular processes involved in WDR34 activation. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A769662 is an AMPK activator that can stimulate AMPK-dependent pathways, potentially influencing WDR34 activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR activates AMPK, which in turn can modulate cellular processes involving WDR34. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Salicylate activates AMPK, a key regulator of energy homeostasis and cellular metabolism, potentially activating WDR34. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates AMPK and SIRT1, which can impact cellular processes involving WDR34. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-Deoxyglucose inhibits glycolysis, leading to AMPK activation and potential modulation of WDR34 activity. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin activates AMPK, which may influence cellular processes involving WDR34. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Oligomycin A inhibits ATP synthase, leading to AMPK activation and potential regulation of WDR34. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG activates AMPK and modulates cellular energy metabolism, potentially influencing WDR34 activity. | ||||||