Date published: 2025-11-1

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Vmn2r86 Inhibitors

The chemical class known as Vmn2r86 Inhibitors encompasses a range of compounds that indirectly target the signaling mechanisms associated with the Vmn2r86 receptor. This receptor, belonging to the vomeronasal type 2 receptor family, plays a crucial role in the detection of pheromonal signals, with its activity being mediated through complex intracellular pathways characteristic of G protein-coupled receptors. Given the absence of direct inhibitors, the strategy employed focuses on modulating the broader signaling landscape within which Vmn2r86 operates. By targeting key regulatory molecules and pathways such as cAMP production, calcium signaling, and various kinase activities, these inhibitors can alter the cellular context and modulate the receptor's function. This approach not only provides insights into the functional modulation of Vmn2r86 but also highlights the intricate web of cellular signaling pathways that govern sensory perception and response mechanisms at the molecular level.

This exploration into the potential modulation of Vmn2r86 through indirect inhibitors exemplifies the complexity of signaling networks and the nuanced strategies required to influence receptor activity. The selected compounds, by acting on various signaling intermediates, offer a toolkit for investigating the physiological roles of Vmn2r86 and the mechanisms by which it contributes to pheromone detection and signaling. Through such investigations, the inhibitors facilitate a deeper understanding of the molecular underpinnings of sensory signaling and the interplay between different signaling modules. This approach underscores the potential of targeted chemical intervention to unravel the signaling dynamics of vomeronasal receptors, providing a foundation for further research into the molecular basis of sensory processes and their regulation.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$285.00
$520.00
$1300.00
78
(4)

Inhibits protein phosphatases PP1 and PP2A, potentially affecting the phosphorylation state crucial for Vmn2r86 signaling.