Vigilin Inhibitors
Vigilin inhibitors belong to a distinct chemical class that has garnered considerable attention in the field of molecular biology and biochemistry. These compounds are characterized by their ability to interact with and modulate the activity of a protein known as Vigilin. Vigilin is a multifunctional protein found in various organisms, including humans, and plays a crucial role in RNA metabolism. The class of Vigilin inhibitors includes a diverse range of small molecules and compounds that have been developed to specifically target and interfere with Vigilin's functions within the cellular environment.
Vigilin inhibitors involves their ability to bind to Vigilin protein, leading to alterations in its conformation or blocking its functional domains. This interaction can disrupt the normal functioning of Vigilin, affecting its RNA-binding capabilities and, consequently, its role in RNA transport, stability, and turnover. By perturbing Vigilin's functions, these inhibitors have been instrumental in elucidating the intricate processes of RNA metabolism and regulation within cells. Researchers have utilized Vigilin inhibitors as valuable tools to unravel the complex networks of RNA-protein interactions and their implications in various cellular pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid found in many fruits and vegetables. It can modulate signal transduction pathways, potentially affecting the mRNA stability and translation in which Vigilin is involved. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is an isoflavone derived from soy products. It acts as a tyrosine kinase inhibitor and can alter phosphorylation cascades, which may indirectly affect Vigilin's RNA-binding capacity. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine is an aminoquinoline known for its interference with lysosomal acidification. It can alter cellular trafficking and endocytosis, processes that may indirectly involve Vigilin's function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a steroidal metabolite that acts as a potent inhibitor of phosphoinositide 3-kinases. It can disrupt various signaling pathways, potentially influencing Vigilin's role in RNA metabolism. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a morpholine derivative that inhibits phosphoinositide 3-kinases. By affecting PI3K-related pathways, it can indirectly influence processes where Vigilin is active. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a synthetic compound that inhibits MEK, which is involved in the MAPK/ERK pathway. It can indirectly affect Vigilin's regulatory mechanisms in mRNA stability. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is another MEK inhibitor that can interfere with the MAPK/ERK pathway. Like PD98059, it can indirectly affect the functional role of Vigilin in cells. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is a macrolide compound that inhibits mTOR, a key regulator of cell growth and proliferation. It can modify the translation of mRNAs, a process where Vigilin may have a role. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a pyridinyl imidazole derivative that selectively inhibits p38 MAP kinase. It can alter stress response pathways and possibly affect Vigilin's function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an anthrapyrazolone inhibitor of JNK, modulating stress response pathways. Its action can have consequences for cellular processes involving Vigilin. | ||||||