vezatin Activators
Adherens junctions are complex protein structures that play a crucial role in cell-cell adhesion, maintaining tissue integrity, and signaling processes. These junctions are especially prominent in epithelial tissues, where they contribute to the structural integrity of tissues by mediating adhesion between neighboring cells. Adherens junctions are composed of various proteins, including transmembrane proteins, such as cadherins, and intracellular proteins that link the junction to the cell's cytoskeleton.
Vezatin, on the other hand, is a protein that has been identified as a component of adherens junctions. It serves as a linker between the transmembrane proteins in the junction and the cytoskeleton, participating in the overall stability and functionality of these cell adhesion complexes. By facilitating the connection between the cell membrane and the cytoskeleton, vezatin contributes to the maintenance of tissue architecture and the regulation of cell signaling events. The intricate interplay of proteins like vezatin within adherens junctions is vital for normal cellular functions and the development and maintenance of tissues in multicellular organisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calpeptin | 117591-20-5 | sc-202516 sc-202516A | 10 mg 50 mg | $121.00 $456.00 | 28 | |
Serves as a Rho GTPase activator, indirectly activating vezatin by inhibiting calpain and cathepsin B, key regulators in cell adhesion processes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Directly activates vezatin by stimulating PKC, a downstream effector in adherens junction signaling, promoting cell adhesion and signaling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Functions as a Wnt signaling activator, indirectly activating vezatin by inhibiting GSK-3β, a key activator in adherens junction dynamics. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
Indirectly activates vezatin by modulating Wnt signaling through GSK-3β inhibition, contributing to adherens junction activation. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Acts as a calcium ionophore, indirectly activating vezatin by inducing Ca2+ influx, a modulator of adherens junctions and cell adhesion. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Activates vezatin indirectly by facilitating calcium ion influx, a critical factor in adherens junction activation and cell adhesion. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Directly activates vezatin by elevating cAMP levels, contributing to cAMP signaling pathways involved in adherens junction activation. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
Acts as a cAMP analog, directly activating vezatin by activating cAMP signaling pathways, influencing adherens junction dynamics. | ||||||