TRNP-1 activators represent a unique category of chemical compounds that have emerged as a subject of interest within the field of molecular biology and genetics. These compounds are specifically designed to modulate the activity of TRNP-1, a protein-coding gene with multifaceted roles in cellular processes. TRNP-1, which stands for Transfer RNA-Protein Nitrosothiol 1, is involved in the regulation of transfer RNA (tRNA) modifications, particularly in the formation of nitrosothiol modifications. These modifications are crucial for tRNA stability and function in protein synthesis. TRNP-1 activators function by targeting specific regulatory elements within the TRNP-1 gene, often found in promoter or enhancer regions, with the primary goal of enhancing its transcription and subsequent translation into functional protein products.
The mechanisms through which TRNP-1 activators exert their effects may vary, but their central purpose is to act as molecular switches, amplifying the activity of TRNP-1. Researchers are continually exploring the potential applications and implications of TRNP-1 activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly in the context of tRNA modification and its role in protein synthesis. This class of compounds holds promise for advancing our knowledge of gene regulation, specifically within the domain of tRNA modifications, offering insights into the intricate mechanisms that underlie the formation of nitrosothiol modifications and the importance of TRNP-1 in various biological contexts. TRNP-1 activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that TRNP-1 plays in cellular processes and tRNA modification.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Betulinic acid can modulate nuclear factor-kappaB (NF-κB) signaling, potentially affecting the transcriptional regulation of genes under control of TMF1. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been shown to influence multiple signaling pathways, including those affecting transcription factors that could alter TMF1-mediated gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major component of green tea, may alter the activity of various transcription factors and could hypothetically affect TMF1-regulated gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can have wide-ranging effects on transcriptional regulation that might interact with TMF1-regulated genes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, genistein may influence signaling pathways that affect transcription factors and regulators, potentially impacting the expression of TMF1-regulated genes. | ||||||
(±)-Hesperetin | 520-33-2 | sc-202647 | 1 g | $46.00 | 4 | |
Hesperetin may affect cellular signaling and transcriptional control, possibly influencing the expression of genes regulated by TMF1. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Indole-3-carbinol can modify estrogen receptor signaling, which could intersect with TMF1-regulated transcription in a way that alters gene expression. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $97.00 $212.00 $500.00 | 11 | |
Kaempferol may modulate transcription factors and signal transduction pathways that could conceivably interact with TMF1-regulated gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can affect glycogen synthase kinase-3 (GSK-3) signaling, which may have downstream effects on transcriptional regulation including that influenced by TMF1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is known to modulate signaling pathways and could affect transcriptional regulation, possibly influencing TMF1 and its associated genes. |