Date published: 2025-9-10

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TRNP-1 Activators

TRNP-1 activators represent a unique category of chemical compounds that have emerged as a subject of interest within the field of molecular biology and genetics. These compounds are specifically designed to modulate the activity of TRNP-1, a protein-coding gene with multifaceted roles in cellular processes. TRNP-1, which stands for Transfer RNA-Protein Nitrosothiol 1, is involved in the regulation of transfer RNA (tRNA) modifications, particularly in the formation of nitrosothiol modifications. These modifications are crucial for tRNA stability and function in protein synthesis. TRNP-1 activators function by targeting specific regulatory elements within the TRNP-1 gene, often found in promoter or enhancer regions, with the primary goal of enhancing its transcription and subsequent translation into functional protein products.

The mechanisms through which TRNP-1 activators exert their effects may vary, but their central purpose is to act as molecular switches, amplifying the activity of TRNP-1. Researchers are continually exploring the potential applications and implications of TRNP-1 activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly in the context of tRNA modification and its role in protein synthesis. This class of compounds holds promise for advancing our knowledge of gene regulation, specifically within the domain of tRNA modifications, offering insights into the intricate mechanisms that underlie the formation of nitrosothiol modifications and the importance of TRNP-1 in various biological contexts. TRNP-1 activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that TRNP-1 plays in cellular processes and tRNA modification.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Betulinic Acid

472-15-1sc-200132
sc-200132A
25 mg
100 mg
$115.00
$337.00
3
(1)

Betulinic acid can modulate nuclear factor-kappaB (NF-κB) signaling, potentially affecting the transcriptional regulation of genes under control of TMF1.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has been shown to influence multiple signaling pathways, including those affecting transcription factors that could alter TMF1-mediated gene expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG, a major component of green tea, may alter the activity of various transcription factors and could hypothetically affect TMF1-regulated gene expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which can have wide-ranging effects on transcriptional regulation that might interact with TMF1-regulated genes.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

As a tyrosine kinase inhibitor, genistein may influence signaling pathways that affect transcription factors and regulators, potentially impacting the expression of TMF1-regulated genes.

(±)-Hesperetin

520-33-2sc-202647
1 g
$46.00
4
(1)

Hesperetin may affect cellular signaling and transcriptional control, possibly influencing the expression of genes regulated by TMF1.

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$38.00
$60.00
$143.00
$306.00
$1012.00
5
(1)

Indole-3-carbinol can modify estrogen receptor signaling, which could intersect with TMF1-regulated transcription in a way that alters gene expression.

Kaempferol

520-18-3sc-202679
sc-202679A
sc-202679B
25 mg
100 mg
1 g
$97.00
$212.00
$500.00
11
(1)

Kaempferol may modulate transcription factors and signal transduction pathways that could conceivably interact with TMF1-regulated gene expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride can affect glycogen synthase kinase-3 (GSK-3) signaling, which may have downstream effects on transcriptional regulation including that influenced by TMF1.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is known to modulate signaling pathways and could affect transcriptional regulation, possibly influencing TMF1 and its associated genes.