Transgelin Activators belong to a chemical class of compounds that play a significant role in modulating the activity of transgelin, a versatile protein that is involved in various cellular processes, particularly those related to the actin cytoskeleton and cell motility. Transgelin is also known by other names, including SM22-alpha and smooth muscle protein 22-alpha. It is found in both smooth muscle and non-muscle cells and plays a critical role in regulating actin dynamics. Actin is a major component of the cytoskeleton, and its polymerization and reorganization are fundamental for various cellular functions, such as cell contraction, migration, and shape changes. Transgelin has been implicated in processes such as smooth muscle contraction, wound healing, and cell migration, where it interacts with actin filaments and influences their organization and stability.
The mechanism of action of Transgelin Activators typically involves binding to specific regions of the transgelin protein, inducing conformational changes that can enhance or inhibit its interactions with actin and other regulatory proteins. By modulating transgelin activity, these activators impact cellular processes that rely on dynamic changes in the actin cytoskeleton, such as cell motility, adhesion, and contractility. Research into Transgelin Activators provides valuable insights into the complex regulatory mechanisms governing the actin cytoskeleton and its role in various physiological and pathological processes. Understanding how these activators interact with transgelin contributes to our knowledge of the intricate processes involved in cell motility and cytoskeletal dynamics.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is known to modulate gene expression and cellular differentiation, potentially influencing transgelin expression by altering transcriptional regulation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol can regulate gene expression and cellular growth. Its role in transgelin expression may be linked to its effects on smooth muscle cells. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
This polyphenol found in green tea exhibits antioxidant properties and may affect transgelin expression through pathways related to oxidative stress response. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
As an oxidative stress agent, hydrogen peroxide can induce a range of cellular responses, potentially upregulating transgelin as part of the stress response mechanism. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a known stimulant, can influence various cellular pathways, potentially affecting transgelin expression through mechanisms related to energy metabolism. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
As a stress-inducing agent, Sodium (meta)arsenite may affect transgelin expression through pathways related to cellular stress and defense mechanisms. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Exposure to cadmium chloride can induce cellular stress responses, potentially influencing transgelin expression as part of the cell's adaptive mechanisms. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a synthetic glucocorticoid, can regulate gene expression and may influence transgelin expression through its effects on cellular signaling pathways. | ||||||