TNP2 Inhibitors
TNP2 inhibitors belong to a class of chemical compounds that have garnered significant attention in the field of molecular biology and pharmacology due to their unique ability to modulate specific cellular processes. These inhibitors are designed to target a specific protein known as TNP2, which plays a crucial role in various cellular functions. TNP2, short for "Transition Nuclear Protein 2," is a nuclear protein found primarily in male germ cells, particularly during spermatogenesis. It is involved in the condensation of chromatin and the packaging of DNA into sperm cells, ultimately contributing to the formation of mature and functional spermatozoa.
The development of TNP2 inhibitors has opened up avenues for researchers to better understand the intricate processes involved in male fertility and reproductive biology. By inhibiting the activity of TNP2, these compounds disrupt the normal chromatin condensation process, potentially leading to alterations in sperm structure and function. This has sparked interest in studying the effects of TNP2 inhibitors on male fertility and exploring their potential applications in contraception and reproductive health.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their disassembly, which can indirectly inhibit the function of proteins reliant on microtubule dynamics. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin and inhibits microtubule formation, potentially affecting proteins associated with microtubule dynamics. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting microtubule polymerization, which can indirectly affect protein functions related to cell structure and transport. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits microtubule assembly, thereby potentially influencing the function of proteins that interact with the cytoskeleton. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $45.00 $79.00 | ||
Combretastatin A4 disrupts microtubule dynamics, which can indirectly influence proteins associated with cell division and structure. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits the growth phase of microtubules, potentially impacting protein functions that are microtubule-dependent. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin interferes with microtubule function by binding to tubulin, which can indirectly affect proteins linked to cell division. | ||||||
Noscapine | 128-62-1 | sc-219418 | 10 mg | $102.00 | ||
Noscapine binds to tubulin and alters microtubule dynamics, which can indirectly affect the activity of proteins associated with microtubules. | ||||||
MCC950 sodium salt | 256373-96-3 | sc-505904 sc-505904A sc-505904B sc-505904C | 5 mg 10 mg 50 mg 100 mg | $112.00 $194.00 $871.00 $1538.00 | 3 | |
Peloruside A stabilizes microtubules, potentially affecting proteins that rely on microtubule dynamics for their function. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Monastrol is a small molecule inhibitor of the kinesin Eg5, which can indirectly impact proteins that depend on kinesin-mediated transport along microtubules. | ||||||