The chemical class known as TMED3 Inhibitors contains a diverse array of substances that can influence the function of the TMED3 protein. These compounds do not directly target TMED3, but they can affect the cellular processes and pathways involving TMED3. Specifically, some of these substances can disrupt the function of the Golgi apparatus and protein trafficking pathways. The alteration of these pathways can impede the normal function of TMED3, which plays a crucial role in the transport of proteins within the cell.
Other compounds within this class can influence the organization and dynamics of the cellular cytoskeleton, which is essential for maintaining the structural integrity of the Golgi apparatus. Changes to the cytoskeleton can affect the function of TMED3. Additionally, some substances within this class can inhibit microtubule polymerization, a process vital for vesicular transport, and thus influence the function of TMED3. Furthermore, there are compounds that can affect specific processes within the endoplasmic reticulum, impacting the role of TMED3 in protein trafficking. Given the role of TMED3 in protein transport, it's clear that the TMED3 Inhibitors class of compounds can play a significant role in modulating cellular transport processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A inhibits ARF, a protein essential for vesicle formation and transport between the endoplasmic reticulum and Golgi. This inhibition disrupts normal protein trafficking, which could possibly inhibit TMED3 function. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is a sodium ionophore that disrupts Golgi function and alters protein secretion pathways, which could possibly inhibit TMED3's function. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds tubulin, inhibiting microtubule polymerization, essential for vesicular transport, which could possibly inhibit TMED3 function. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D disrupts actin filament organization, which is critical for maintaining Golgi structure and function, and could possibly inhibit TMED3. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Jasplakinolide binds to actin monomers, preventing their polymerization into filaments, which could possibly disrupt Golgi structure and function, thus inhibiting TMED3. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, a modification that happens in the ER and Golgi, which could possibly inhibit TMED3's function in protein trafficking. | ||||||