Date published: 2025-11-1

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THSD7A Inhibitors

THSD7A inhibitors constitute a category of chemical compounds designed to target and inhibit the activity of the THSD7A protein. THSD7A, also known as Thrombospondin Type-1 Domain-Containing 7A, is a protein found in various tissues and plays diverse roles in cellular processes, including cell adhesion, migration, and angiogenesis. Inhibitors of THSD7A are primarily developed and employed in research settings to investigate the fundamental biological functions associated with this protein. These inhibitors serve as valuable tools for molecular biologists and cell biologists aiming to explore the intricate mechanisms underlying cell adhesion, tissue development, and other processes where THSD7A is involved.

THSD7A inhibitors are typically small molecules or chemical compounds that interact with the THSD7A protein, interfering with its normal function. By inhibiting THSD7A, these compounds can modulate processes related to cell adhesion, angiogenesis, and tissue remodeling, providing researchers with insights into the consequences of such disruptions on cellular behavior and tissue development. Scientists use THSD7A inhibitors in laboratory settings to probe the specific functions of THSD7A within cells and tissues, shedding light on the role this protein plays in various physiological processes. While THSD7A inhibitors may have potential applications beyond basic research, their primary purpose is to aid scientists in deciphering the molecular intricacies of THSD7A-mediated cellular functions.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

An anthracycline that intercalates DNA, potentially reducing THSD7A transcription as part of a broader suppression of gene expression.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

A dihydrofolate reductase inhibitor that may lead to decreased nucleotide synthesis and overall reduction in gene expression, including THSD7A.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

An inosine monophosphate dehydrogenase inhibitor that could potentially reduce the expression of multiple genes, including THSD7A.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Inhibits eukaryotic protein synthesis by preventing translational elongation, which would indirectly reduce THSD7A protein levels.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Binds to DNA and disrupts RNA synthesis, which could decrease the transcription of many genes, including THSD7A.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

A signaling molecule that can modulate gene expression, potentially affecting the transcription of THSD7A.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

A histone deacetylase inhibitor that can change chromatin structure and gene expression, potentially impacting THSD7A transcription.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that could cause hypomethylation of gene promoters, potentially downregulating THSD7A expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Similar to 5-Azacytidine, this compound could lead to promoter demethylation and subsequent transcriptional repression of THSD7A.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

A proteasome inhibitor that can affect various signaling pathways, potentially leading to reduced expression of THSD7A.