THSD7A inhibitors constitute a category of chemical compounds designed to target and inhibit the activity of the THSD7A protein. THSD7A, also known as Thrombospondin Type-1 Domain-Containing 7A, is a protein found in various tissues and plays diverse roles in cellular processes, including cell adhesion, migration, and angiogenesis. Inhibitors of THSD7A are primarily developed and employed in research settings to investigate the fundamental biological functions associated with this protein. These inhibitors serve as valuable tools for molecular biologists and cell biologists aiming to explore the intricate mechanisms underlying cell adhesion, tissue development, and other processes where THSD7A is involved.
THSD7A inhibitors are typically small molecules or chemical compounds that interact with the THSD7A protein, interfering with its normal function. By inhibiting THSD7A, these compounds can modulate processes related to cell adhesion, angiogenesis, and tissue remodeling, providing researchers with insights into the consequences of such disruptions on cellular behavior and tissue development. Scientists use THSD7A inhibitors in laboratory settings to probe the specific functions of THSD7A within cells and tissues, shedding light on the role this protein plays in various physiological processes. While THSD7A inhibitors may have potential applications beyond basic research, their primary purpose is to aid scientists in deciphering the molecular intricacies of THSD7A-mediated cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
An anthracycline that intercalates DNA, potentially reducing THSD7A transcription as part of a broader suppression of gene expression. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
A dihydrofolate reductase inhibitor that may lead to decreased nucleotide synthesis and overall reduction in gene expression, including THSD7A. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
An inosine monophosphate dehydrogenase inhibitor that could potentially reduce the expression of multiple genes, including THSD7A. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by preventing translational elongation, which would indirectly reduce THSD7A protein levels. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and disrupts RNA synthesis, which could decrease the transcription of many genes, including THSD7A. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A signaling molecule that can modulate gene expression, potentially affecting the transcription of THSD7A. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can change chromatin structure and gene expression, potentially impacting THSD7A transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that could cause hypomethylation of gene promoters, potentially downregulating THSD7A expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-Azacytidine, this compound could lead to promoter demethylation and subsequent transcriptional repression of THSD7A. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can affect various signaling pathways, potentially leading to reduced expression of THSD7A. | ||||||