TCEA3 Activators
Transcription elongation factor A protein 3 (TCEA3) is a protein that in humans is encoded by the TCEA3 gene. This protein is part of the transcription elongation factor A (SII) family, which act as essential regulators of transcription elongation by RNA polymerase II, the enzyme responsible for synthesizing messenger RNA in eukaryotes.TCEA3 is involved in the regulation of transcription, a fundamental process where genetic information stored in DNA is transferred to RNA. During transcription, RNA polymerase II can pause or stall, and transcription elongation factors like TCEA3 help the enzyme to continue transcribing.
The TCEA family of proteins interact directly with RNA polymerase II and can influence the fidelity of transcription by controlling the rate at which the enzyme moves along the DNA template. By doing so, they play a crucial role in ensuring that genes are accurately and efficiently transcribed into RNA.However, given the essential function of transcription and the role TCEA proteins play in this process, it is conceivable that alterations in TCEA3 could have significant effects on gene expression and cellular function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
SAHA, another HDAC inhibitor, could affect chromatin remodeling and indirectly influence TCEA3 activity. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
DRB inhibits RNA Polymerase II transcription elongation and might provide insights into TCEA3-mediated transcription processes. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor, potentially impacting transcription regulation pathways involving TCEA3. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
MS-275 selectively inhibits Class I HDACs, potentially influencing chromatin structure and TCEA3 activity. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds to DNA and inhibits RNA synthesis, potentially affecting transcription processes regulated by TCEA3. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Mithramycin A binds to DNA and inhibits RNA polymerase, potentially impacting TCEA3-mediated transcription. | ||||||
SGC-CBP30 | 1613695-14-9 | sc-473871 sc-473871A | 5 mg 10 mg | $178.00 $338.00 | ||
SGC-CBP30 is a CBP/p300 inhibitor, potentially affecting transcription factors and coactivators interacting with TCEA3. | ||||||