TAFA1 activators represent a unique category of chemical compounds designed to modulate the activity of the protein encoded by the TAFA1 gene. This gene is a member of the FAM19A family and is recognized as an open reading frame (ORF) in the human genome. The precise biological function of the TAFA1 protein remains largely uncharacterized, and its role within cellular processes is not well understood. Activators of TAFA1 have been developed to explore the potential roles and regulatory mechanisms associated with this protein. By enhancing the activity or influencing the interactions of TAFA1, these compounds provide a valuable tool for investigating its potential involvement in cellular signaling, protein-protein interactions, or other essential biological functions. The study of TAFA1 activators contributes to a deeper understanding of gene function and its implications for cellular physiology and molecular biology.
The investigation of TAFA1 activators is a multidisciplinary endeavor that combines principles from synthetic chemistry, molecular biology, and cell biology. To develop these compounds, researchers require a comprehensive understanding of the TAFA1 protein, including its structural domains and potential interaction partners within the cellular context. The identification of molecules capable of specifically enhancing the activity or interactions of TAFA1 involves screening chemical libraries for compounds that can bind to the protein or modulate its function. This research entails in vitro assays to assess changes in protein activity or interactions, as well as cellular studies to observe the effects of TAFA1 activation on broader physiological processes. Techniques such as mass spectrometry for protein interaction analysis, fluorescence microscopy for cellular localization studies, and functional assays to evaluate cellular responses may be employed to elucidate the functional consequences of activating TAFA1. Through these comprehensive investigations, researchers aim to uncover the biological significance of TAFA1 and its potential role in cellular processes, contributing to the ongoing exploration of gene function within the human genome.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, resulting in increased cAMP levels, which may upregulate gene expression through the activation of PKA and CREB transcription factors. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid acts on retinoic acid receptors, influencing gene transcription in a manner that could potentially induce the expression of genes like TAFA1. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 engages the vitamin D receptor, affecting the transcription of genes with vitamin D response elements in their promoters. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA is a histone deacetylase inhibitor that can upregulate gene expression by altering chromatin structure and making DNA more accessible for transcription. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This compound is a DNA methyltransferase inhibitor, potentially increasing gene expression by reducing DNA methylation. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can inhibit GSK-3β, possibly leading to altered gene expression through Wnt signaling and other pathways. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Beta-estradiol can bind estrogen receptors, potentially affecting the transcription of estrogen-responsive genes. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
db-cAMP is a cell-permeable cAMP analog that may mimic cAMP's effect on gene expression by activating PKA and related transcription factors. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor that may promote gene expression by affecting chromatin structure. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone is a PPARγ agonist that can modulate gene expression by activating PPARγ receptors. | ||||||