Date published: 2026-5-15

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Tachykinin 4 Activators

Tachykinin 4 activators comprise a range of chemical compounds that indirectly enhance the activity of Tachykinin 4 by interfacing with various cellular signaling pathways. For instance, Forskolin elevates cyclic AMP levels, which subsequently activates PKA. The activated PKA may phosphorylate substrates that are part of the Tachykinin 4 signaling cascade, thereby increasing its functional activity. Nicotine, by stimulating nicotinic acetylcholine receptors, can lead to the upregulation of neuropeptide release, including Tachykinin 4, effectively enhancing its signaling potential in neural communication. Capsaicin engages with the TRPV1 receptor, triggering the release of neuropeptides such as Tachykinin 4, augmenting its functional role in pain and inflammation pathways. Resveratrol activates SIRT1, potentially influencing the signaling pathways that upregulate Tachykinin 4 function. Moreover, agents like Zinc, Sodium Butyrate, and Nitric Oxide Donor can modulate synaptic transmission and neurochemical pathways, leading to an increase in Tachykinin 4 activity indirectly.

Furthermore, excitatory neurotransmitters like Kainic Acid and NMDA, by activating their respective receptors, could enhance the release of Tachykinin 4 through excitatory synaptic transmission. Serotonin, a key neurotransmitter, might also elevate the function of Tachykinin 4 through its diverse set of receptors, indicating a role in neuromodulation where Tachykinin 4 is active. Additionally, ATP, as an extracellular signaling molecule, can activate purinergic receptors influencing neuronal communication and potentially enhancing Tachykinin 4 signaling. Lastly, GABA, often recognized for its inhibitory action in the CNS, may exert a nuanced effect on the release of neuropeptides like Tachykinin 4, suggesting a complex interplay where GABAergic signaling can indirectly lead to Tachykinin 4 activation.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin is a labdane diterpene that activates the enzyme adenylyl cyclase, leading to an increase in cyclic AMP (cAMP) levels in cells. Elevated cAMP activates protein kinase A (PKA), which can phosphorylate various targets potentially enhancing Tachykinin 4 signaling by promoting downstream neurological processes that Tachykinin 4 is involved in.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin is an active component of chili peppers which binds to the transient receptor potential vanilloid 1 (TRPV1). Activation of TRPV1 on sensory neurons can lead to the release of neuropeptides including Tachykinin 4, thus enhancing its functional activity in pain and inflammation pathways.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc is a trace element that can act as a neuromodulator in the central nervous system. It can influence synaptic transmission and might enhance the release of Tachykinin 4 by modulating the activity of neurotransmitter systems that regulate its secretion.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a polyphenolic compound that activates sirtuin 1 (SIRT1), which has been implicated in the modulation of neurotransmitter systems. Activation of SIRT1 may enhance the signaling pathways that lead to the release or activity of Tachykinin 4.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate is a short-chain fatty acid that acts as a histone deacetylase inhibitor. While it primarily influences gene expression, it can also affect neurotransmission, potentially leading to an increased activity of Tachykinin 4 in neuronal communication.

Kainic acid

487-79-6sc-200454
sc-200454A
sc-200454B
sc-200454C
sc-200454D
5 mg
25 mg
100 mg
1 g
5 g
$87.00
$370.00
$1377.00
$7803.00
$24970.00
12
(1)

Kainic acid is an agonist of the kainate class of ionotropic glutamate receptors. Its excitatory action on neurons may enhance the release of neuropeptides like Tachykinin 4 as part of the excitatory neurotransmission process.

N-Methyl-D-Aspartic acid (NMDA)

6384-92-5sc-200458
sc-200458A
50 mg
250 mg
$109.00
$369.00
2
(1)

NMDA is an agonist for the N-methyl-D-aspartate receptor, a subtype of glutamate receptor. NMDA receptor activation results in excitatory synaptic transmission which could facilitate the release of Tachykinin 4 in neuronal pathways.

Serotonin hydrochloride

153-98-0sc-201146
sc-201146A
100 mg
1 g
$118.00
$187.00
15
(1)

Serotonin is a monoamine neurotransmitter that can modulate the activity of certain neurons. Through its action on serotonin receptors, it may enhance the release or function of Tachykinin 4 in pathways where they coexist or have a functional overlap.

Sodium nitroprusside dihydrate

13755-38-9sc-203395
sc-203395A
sc-203395B
1 g
5 g
100 g
$43.00
$85.00
$158.00
7
(1)

Sodium nitroprusside releases nitric oxide (NO), which serves as a neuromodulator or neurotransmitter in the central nervous system. NO can modulate neuronal signaling and potentially enhance the activity of neuropeptides like Tachykinin 4.

Adenosine 5′-Triphosphate, disodium salt

987-65-5sc-202040
sc-202040A
1 g
5 g
$39.00
$75.00
9
(1)

ATP serves as a neurotransmitter in both central and peripheral nervous systems. Through purinergic receptors, ATP can modulate neuronal activity, which may include the promotion of Tachykinin 4 release or signaling in various neuronal pathways.