Swe1 activators encompass a diverse array of chemicals that, through various mechanisms, contribute to the upregulation of the Swe1 protein, a crucial regulator involved in cell cycle progression in yeast. These activators often interact with different cellular pathways and molecular targets, subtly influencing the regulatory networks that control the expression and activity of Swe1. For instance, some compounds in this class may target histone modifiers, such as histone deacetylases (HDACs), influencing chromatin accessibility and transcriptional activity of genes, including those involved in the production of Swe1. Others may interact with cellular stress response pathways, modulating the cellular environment to create conditions conducive to the enhanced expression of Swe1 as part of a broader adaptive response.
Notably, the Swe1 activators do not typically act directly on Swe1 itself but instead modulate broader cellular mechanisms that indirectly influence Swe1 expression levels. These chemicals may impact protein stability, degradation pathways, or interact with other proteins and enzymes that are upstream regulators of Swe1. The diversity in the mechanisms of action of these activators reflects the complexity of cellular regulation and the multifaceted control of protein expression and activity. Understanding the varied actions of these activators helps elucidate the intricate web of regulatory interactions and environmental responses that shape the functional expression of Swe1 in cellular processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor that promotes a more relaxed chromatin state, potentially increasing transcription of target genes including Swe1. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Another HDAC inhibitor. By altering chromatin structure, it can promote transcription of certain genes. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
HSP90 inhibitor. Might affect Swe1 stability or expression by disrupting protein folding and maturation processes. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
Inhibits HSP90, potentially affecting the stability or expression of proteins, including Swe1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor. By influencing protein synthesis rates, it might affect Swe1 expression. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Another mTOR inhibitor. Can modulate protein synthesis and potentially influence Swe1 levels. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Induces replication stress, potentially enhancing Swe1 expression as part of the cell's stress response. | ||||||