SUV39H1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
Chaetocin (CAS 28097-03-2) is a mycotoxin found in Chaetomium fungi. As a histone methyltransferase inhibitor, it specifically inhibits SUV39H1, impacting histone methylation and gene expression. This action can influence various cellular processes, providing a tool for studying epigenetic mechanisms. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $36.00 $110.00 $400.00 | ||
BIX01294 hydrochloride is a diazepin-quinazolin-amine derivative that selectively inhibits SUV39H1, leading to a decrease in histone H3 lysine 9 methylation. It targets the SET domain of the enzyme, disrupting its function. | ||||||
A-366 | 1527503-11-2 | sc-507495 | 10 mg | $195.00 | ||
A-366 selectively inhibits SUV39H1, resulting in reduced levels of H3K9me3, a marker of gene repression. It binds to the catalytic domain of SUV39H1, impairing its methyltransferase activity. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
UNC0638 is a potent and selective inhibitor of SUV39H1, reducing global levels of H3K9me2 and H3K9me3 without affecting other histone methyltransferases. It interacts with the SET domain, leading to impaired SUV39H1 activity. | ||||||
PF 477736 | 952021-60-2 | sc-362781 sc-362781A | 5 mg 25 mg | $113.00 $423.00 | ||
PF-477736 selectively inhibits SUV39H1, leading to reduced H3K9me3 levels and altered chromatin structure. While it primarily targets DNA damage checkpoint kinases, it also impacts SUV39H1 activity. | ||||||
Quinacrine, Dihydrochloride | 69-05-6 | sc-204222 sc-204222B sc-204222A sc-204222C sc-204222D | 100 mg 1 g 5 g 200 g 300 g | $45.00 $56.00 $85.00 $3193.00 $4726.00 | 4 | |
Quinacrine has been found to indirectly influence SUV39H1 activity and reduce H3K9 methylation, possibly through interaction with DNA or chromatin remodeling complexes. | ||||||
1-Hydrazinophthalazine Hydrochloride | 304-20-1 | sc-206167 | 10 g | $280.00 | ||
1-Hydrazinophthalazine Hydrochloride, an antihypertensive agent, has demonstrated potential in reducing SUV39H1 expression and activity, leading to alterations in histone methylation and gene expression. Its effect on SUV39H1 is likely indirect, possibly through epigenetic modifications. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2'-deoxycytidine, a DNA methyltransferase inhibitor, can indirectly reduce SUV39H1 expression and affect histone methylation patterns, leading to changes in gene expression. | ||||||