Sodium Channel Modulators
Items 71 to 74 of 74 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pentisomide | 78833-03-1 | sc-219569 | 2.5 mg | $430.00 | ||
Pentisomide acts as a sodium channel modulator by engaging with specific allosteric sites, which induces conformational changes in the channel structure. Its unique molecular interactions facilitate a nuanced alteration in ion permeability, impacting the channel's gating dynamics. The compound's distinctive electronic properties enhance its affinity for the channel, promoting a tailored modulation of sodium ion flow, thereby influencing cellular excitability and signaling pathways. | ||||||
Amiloride-15N3 Hydrochloride | 1216796-18-7 | sc-217623 | 5 mg | $3000.00 | ||
Amiloride-15N3 Hydrochloride functions as a sodium channel modulator by selectively binding to the channel's extracellular domain, leading to a reduction in sodium ion influx. Its nitrogen isotope labeling allows for precise tracking in biochemical studies, enhancing understanding of ion transport mechanisms. The compound's unique steric configuration influences its interaction kinetics, resulting in a distinct modulation profile that alters channel activity and ion homeostasis. | ||||||
Lamotrigine isethionate | 113170-86-8 | sc-218654 | 10 mg | $260.00 | ||
Lamotrigine isethionate acts as a sodium channel modulator by engaging with the channel's voltage-sensing domains, stabilizing the inactivated state and thereby reducing excitability. Its unique isethionate moiety enhances solubility and facilitates specific interactions with lipid membranes, influencing membrane fluidity. The compound exhibits distinct reaction kinetics, characterized by a rapid onset and prolonged duration of action, which can affect the overall dynamics of sodium ion conductance. | ||||||
NS8593 hydrochloride | 875755-24-1 | sc-253203 | 5 mg | $210.00 | 1 | |
NS8593 hydrochloride functions as a sodium channel modulator by selectively binding to the channel's inactivation gate, promoting a state that limits ion flow. Its unique structural features allow for enhanced affinity towards specific channel subtypes, influencing gating kinetics. The compound's interactions with lipid bilayers can alter membrane potential dynamics, while its distinct physicochemical properties contribute to its modulation efficacy, impacting sodium ion permeability in various cellular environments. | ||||||