Smarcad1 Inhibitors
Smarcad1 Inhibitors is a term that refers to a group of chemical compounds designed to reduce or hinder the activity of the Smarcad1 protein. Smarcad1, or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin, subfamily A, containing DEAD/H box 1, plays a key role in chromatin remodeling processes, contributing to various cellular events including DNA repair, embryonic stem cell differentiation, and the epigenetic control of gene expression. By inhibiting the function or expression of Smarcad1, these inhibitors aim to influence chromatin organization and related cellular mechanisms.
The chemical structures and functionalities of Smarcad1 inhibitors can vary widely. Their design often stems from an understanding of the protein's structure and its interaction with DNA or other binding partners. By targeting specific domains or active sites of the protein, these inhibitors can impede Smarcad1 from fulfilling its role in chromatin remodeling. Furthermore, some inhibitors may act indirectly, affecting upstream or downstream pathways that modulate the expression or activity of Smarcad1. It's important to note that while some compounds, like those mentioned earlier, might have effects on Smarcad1 expression or function, not all of them were originally designed with the sole purpose of inhibiting Smarcad1. Research into these inhibitors is driven by a desire to better understand cellular mechanisms, the role of chromatin dynamics in cellular events, and the consequences of modulating Smarcad1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin, an anthracycline antibiotic, has been shown to affect several genes' expression, including those involved in chromatin remodeling. While its primary mode of action is intercalation into DNA, it may indirectly influence Smarcad1 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a potent inhibitor of histone deacetylases. By influencing histone acetylation levels, it can impact chromatin structure and consequently the expression of genes like Smarcad1. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can induce differentiation in various cell types and affect gene expression patterns. Its influence on signaling pathways might indirectly modulate Smarcad1 levels. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine, like 5-Azacytidine, is a cytidine analog causing DNA hypomethylation. It can thus change gene expression patterns, potentially affecting Smarcad1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is an inhibitor of histone deacetylases. By affecting acetylation patterns, it can influence the chromatin structure and potentially alter Smarcad1 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been suggested to influence various signaling pathways and can affect the expression of numerous genes. Its broad impacts might include modulation of Smarcad1. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a cyclin-dependent kinase inhibitor. By influencing cell cycle progression, it may indirectly modulate the expression of genes like Smarcad1. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram has been proposed to affect the proteasome and protein degradation pathways. Its influence on these pathways might indirectly affect Smarcad1 levels. | ||||||
ACY-1215 | 1316214-52-4 | sc-507455 | 25 mg | $110.00 | ||
Rocilinostat is an inhibitor of histone deacetylase 6 (HDAC6). By influencing histone acetylation, it may have downstream effects on genes like Smarcad1. | ||||||