SLC22A11 Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Novobiocin | 303-81-1 | sc-362034 sc-362034A | 5 mg 25 mg | $96.00 $355.00 | ||
Novobiocin acts as a selective inhibitor of the SLC22A11 transporter, engaging in specific molecular interactions that disrupt substrate binding. Its unique structure allows for competitive inhibition, altering the transport kinetics of organic anions. The compound's hydrophilic regions enhance solubility, while its distinct conformational flexibility enables it to adapt to various binding sites, influencing its interaction dynamics with cellular membranes and transport proteins. | ||||||
Probenecid | 57-66-9 | sc-202773 sc-202773A sc-202773B sc-202773C | 1 g 5 g 25 g 100 g | $27.00 $38.00 $98.00 $272.00 | 28 | |
Probenecid inhibits organic anion transporters (OATs) and can inhibit SLC22A11 by competitively binding to the same substrate recognition sites, thus preventing the transport of endogenous and exogenous anions. | ||||||
Benzbromarone | 3562-84-3 | sc-233934 sc-233934A | 1 g 5 g | $52.00 $219.00 | ||
Benzbromarone inhibits urate transporter proteins, and by this action, it can inhibit SLC22A11 by competing with its substrates, leading to a decrease in the protein's transport activity. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $28.00 $37.00 | 18 | |
Indomethacin, a nonsteroidal anti-inflammatory drug, can inhibit SLC22A11 by binding to its substrate recognition sites, thereby disrupting the normal transport function of the protein through competitive inhibition. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
Ibuprofen can inhibit SLC22A11 by competing with the natural substrates of the transporter for binding, thereby reducing the transporter's ability to function. | ||||||
Ketoprofen | 22071-15-4 | sc-205359 sc-205359A | 5 g 25 g | $93.00 $308.00 | 2 | |
Ketoprofen inhibits SLC22A11 by competing with its substrates for transport, effectively reducing the capacity of SLC22A11 to carry out its role in anion transport. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Losartan can inhibit SLC22A11 through competition for the anion transport sites, blocking the binding and translocation of other substrates that are normally transported by this protein. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
Cimetidine is known to inhibit various organic cation transporters and can inhibit SLC22A11 by competing with the transporters' natural substrates, therefore blocking its transport function. | ||||||
Phenylbutazone | 50-33-9 | sc-204843 | 5 g | $31.00 | 1 | |
Phenylbutazone can inhibit SLC22A11 function by binding to the transporter and preventing the entry or exit of physiological substrates, thus acting as a competitive inhibitor. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $252.00 $495.00 | 9 | |
Atorvastatin, a statin medication, can inhibit SLC22A11 by competing with endogenous substrates for transport sites, which would reduce the protein's transport activity. | ||||||