SK1 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Naphtho[1,2-d]thiazol-2-ylamine | 40172-65-4 | sc-279906 | 1 g | $245.00 | ||
Naphtho[1,2-d]thiazol-2-ylamine (CAS 40172-65-4) is a chemical compound known for its inhibitory activity against SK1 (sphingosine kinase 1), an enzyme involved in cellular signaling pathways. It exhibits potential as an SK1 inhibitor in preclinical research. | ||||||
1-EBIO | 10045-45-1 | sc-201695 sc-201695A | 10 mg 50 mg | $87.00 $325.00 | 1 | |
1-Ethyl-2-benzimidazolinone (1-EBIO) enhances the activity of Small conductance calcium-activated potassium channel protein 1 by acting as a channel opener. It increases the channel's sensitivity to calcium, leading to more frequent channel activation. | ||||||
PNU 120596 | 501925-31-1 | sc-203200 sc-203200A | 1 mg 5 mg | $32.00 $84.00 | 1 | |
NS8593 is a negative modulator of the calcium sensitivity of Small conductance calcium-activated potassium channel protein 1. By decreasing calcium sensitivity, it can indirectly increase channel activity under high intracellular calcium conditions. | ||||||
Apamin | 24345-16-2 | sc-200994 sc-200994A | 500 µg 1 mg | $171.00 $286.00 | 7 | |
Apamin is a bee venom peptide that blocks Small conductance calcium-activated potassium channel protein 1. Its blocking action can increase the intracellular calcium concentration, which indirectly enhances the channel's probability to open once unblocked. | ||||||
NS 1643 | 448895-37-2 | sc-204135 sc-204135A | 10 mg 50 mg | $123.00 $473.00 | 3 | |
NS1643 is a compound that increases the open probability of Small conductance calcium-activated potassium channel protein 1 by lengthening the duration of its open state, thus raising the overall potassium ion flow. | ||||||
Riluzole | 1744-22-5 | sc-201081 sc-201081A sc-201081B sc-201081C | 20 mg 100 mg 1 g 25 g | $20.00 $193.00 $213.00 $317.00 | 1 | |
Riluzole is known to enhance the activity of Small conductance calcium-activated potassium channel protein 1 by modulating its gating properties, thus facilitating an increased potassium current. | ||||||
Bicalutamide | 90357-06-5 | sc-202976 sc-202976A | 100 mg 500 mg | $42.00 $146.00 | 27 | |
DCEBIO is a synthetic molecule that activates Small conductance calcium-activated potassium channel protein 1 by increasing the sensitivity of the channels to calcium ions, leading to enhanced channel opening. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $104.00 | 3 | |
Quinidine is primarily a potassium channel blocker, but its binding can indirectly lead to the activation of compensatory regulatory mechanisms that enhance Small conductance calcium-activated potassium channel protein 1 activity. | ||||||