Sigma Receptor Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Naloxone hydrochloride | 357-08-4 | sc-203153 sc-203153A sc-203153B sc-203153C | 50 mg 100 mg 1 g 10 g | $85.00 $166.00 $335.00 $1827.00 | 2 | |
Naloxone hydrochloride may inhibits Sigma Receptor by binding to its active site or interacting with its binding site, disrupting the receptor's normal function. This interference can impact downstream signaling and cellular processes regulated by the Sigma Receptor. | ||||||
BD 1047 dihydrobromide | 138356-21-5 | sc-203837 sc-203837A | 10 mg 50 mg | $142.00 $597.00 | 4 | |
This compound may bind to the sigma-1 receptor's active site or its binding pocket. By doing so, it competitively blocks the binding of endogenous ligands or other molecules that would normally interact with the receptor. | ||||||
NE 100 hydrochloride | 149409-57-4 | sc-204121 sc-204121A sc-204121B sc-204121C sc-204121D | 10 mg 50 mg 500 mg 1 g 10 g | $162.00 $683.00 $4080.00 $7140.00 $64566.00 | 21 | |
NE 100 hydrochloride exhibits a remarkable affinity for sigma receptors, characterized by its unique ability to stabilize receptor conformations through specific electrostatic interactions. This compound demonstrates distinct kinetic properties, allowing for rapid binding and unbinding, which may influence receptor activation states. Its molecular architecture promotes effective hydrophobic interactions, enhancing membrane permeability and facilitating nuanced modulation of intracellular signaling cascades. | ||||||
BD 1063 dihydrochloride | 206996-13-6 | sc-203838 sc-203838A sc-203838B sc-203838C sc-203838D | 10 mg 50 mg 1.5 g 2 g 3 g | $145.00 $500.00 $5000.00 $5700.00 $6533.00 | 1 | |
BD 1063 dihydrochloride is notable for its selective engagement with sigma receptors, showcasing a unique binding profile that alters receptor dynamics. Its structure enables specific hydrogen bonding and hydrophobic interactions, which contribute to its stability in biological environments. The compound's kinetic behavior is marked by a slow dissociation rate, allowing for prolonged receptor occupancy. This characteristic may lead to intricate modulation of downstream signaling pathways, influencing cellular responses. | ||||||
SM-21 maleate | 155058-71-2 | sc-204289 sc-204289A | 10 mg 50 mg | $154.00 $638.00 | 1 | |
SM-21 maleate exhibits a distinctive affinity for sigma receptors, characterized by its ability to induce conformational changes in receptor structure upon binding. This compound facilitates unique electrostatic interactions that enhance receptor-ligand stability. Its reaction kinetics reveal a rapid association phase, followed by a gradual equilibrium, which may influence the receptor's regulatory mechanisms. Additionally, SM-21 maleate's solubility properties allow for effective distribution in various environments, impacting its interaction dynamics. | ||||||
BD 1008 Dihydrobromide | 138356-09-9 | sc-207316 | 10 mg | $140.00 | ||
BD 1008 Dihydrobromide demonstrates a notable selectivity for sigma receptors, engaging in specific hydrogen bonding and hydrophobic interactions that stabilize its binding. This compound exhibits a unique allosteric modulation effect, altering receptor activity through conformational shifts. Its kinetic profile indicates a biphasic binding mechanism, with an initial fast phase followed by a slower dissociation, suggesting potential for prolonged receptor engagement. The compound's solubility characteristics further enhance its interaction potential across diverse biological systems. | ||||||
BD 1008 | 138356-08-8 | sc-203426 sc-203426A | 10 mg 50 mg | $200.00 $525.00 | ||
BD 1008 is characterized by its distinctive affinity for sigma receptors, where it engages in intricate electrostatic interactions that facilitate receptor activation. This compound exhibits a unique dual-binding mode, allowing it to influence receptor dynamics through both competitive and non-competitive pathways. Its reaction kinetics reveal a rapid association phase, followed by a gradual stabilization, indicating a complex interplay with receptor conformations. Additionally, BD 1008's lipophilicity enhances its membrane permeability, promoting effective receptor engagement. | ||||||
Metaphit methanesulfonate salt | 99287-12-4 | sc-253003 | 25 mg | $186.00 | ||
Metaphit methanesulfonate salt demonstrates a remarkable selectivity for sigma receptors, engaging in specific hydrogen bonding and hydrophobic interactions that modulate receptor activity. Its unique structural features enable it to adopt multiple conformations, influencing receptor signaling pathways. The compound exhibits a notable rate of dissociation, suggesting a dynamic equilibrium with receptor states. Furthermore, its solubility profile enhances its interaction potential within biological membranes, facilitating nuanced receptor modulation. | ||||||