Date published: 2026-5-14

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SH3BGRL Activators

The SH3 domain-binding glutamate-rich protein like (SH3BGRL) is a member of a family of proteins that are known for their involvement in various cellular processes. SH3BGRL, in particular, has been implicated in cell growth, differentiation, and intracellular signaling pathways. It is thought to play a crucial role in maintaining cellular homeostasis and its dysregulation has been associated with several pathological conditions. However, the specific pathways and mechanisms through which SH3BGRL exerts its effects are not fully understood and remain an active area of investigation.

A variety of chemicals, primarily found in natural compounds, have been identified as modulators of SH3BGRL expression. For instance, retinoic acid, a metabolite of Vitamin A, is known for its role in cell growth and differentiation, and could upregulate SH3BGRL. Curcumin, a polyphenolic compound from turmeric, can modulate intracellular signaling pathways that may influence the expression of SH3BGRL. Similarly, epigallocatechin gallate (EGCG), a catechin found in green tea, has the ability to modulate multiple cellular pathways, which may impact SH3BGRL expression. Other compounds like sulforaphane, quercetin, indole-3-carbinol, genistein, lycopene, zerumbone, ellagic acid, and capsaicin have also been hypothesized to influence SH3BGRL expression through their effects on various cellular mechanisms. It's important to note that while these compounds have been associated with the modulation of SH3BGRL expression, these associations warrant further research for confirmation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, a metabolite of Vitamin A, is known for its role in cell growth and differentiation. It has the potential to upregulate SH3BGRL, given the protein's possible involvement in similar biological processes.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, a polyphenolic compound from turmeric, may modulate intracellular signaling pathways. This could potentially lead to the upregulation of proteins like SH3BGRL, which are thought to be involved in similar pathways.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

(-)-Epigallocatechin Gallate, a catechin found in green tea, has the ability to modulate multiple cellular pathways. It could potentially induce the expression of SH3BGRL, given the protein's potential role in similar cellular processes.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

DL-Sulforaphane, a compound prevalent in cruciferous vegetables, is known to activate cellular defense mechanisms. This could potentially lead to the upregulation of proteins like SH3BGRL, which are involved in cellular growth and differentiation.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin, a flavonoid found in many plants and foods, can influence various cellular signaling pathways. It could possibly induce the expression of SH3BGRL, aligning with the protein's potential role in similar signaling pathways.

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$39.00
$61.00
$146.00
$312.00
$1032.00
5
(1)

Indole-3-carbinol, found in glucobrassicin in cruciferous vegetables, modulates cellular pathways. It could potentially lead to the upregulation of SH3BGRL, given the protein's potential involvement in similar cellular processes.

Lycopene

502-65-8sc-205738
sc-205738A
sc-205738B
1 mg
5 mg
1 g
$146.00
$582.00
$6248.00
4
(1)

Lycopene, a carotenoid found in tomatoes, may affect cell growth and differentiation. It might potentially upregulate SH3BGRL, given the protein's suggested involvement in these biological processes.

Zerumbone

471-05-6sc-364148
sc-364148A
10 mg
50 mg
$112.00
$408.00
(0)

Zerumbone, a bioactive compound from ginger, has been shown to modulate cellular pathways. It might potentially induce the expression of SH3BGRL, given the protein's potential role in similar cellular processes.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic acid, a polyphenol found in various fruits, can influence signaling pathways. It could potentially lead to the upregulation of SH3BGRL, aligning with the protein's potential role in similar signaling pathways.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin, the active component of chili peppers, can influence cellular mechanisms. It might potentially upregulate SH3BGRL, given the protein's potential involvement in similar biological processes.