RXR Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
9-cis-Retinoic acid serves as a potent ligand for retinoid X receptors (RXRs), facilitating the formation of heterodimers with other nuclear receptors. This compound exhibits unique conformational flexibility, allowing it to engage in specific hydrogen bonding and hydrophobic interactions that stabilize receptor complexes. Its influence on gene expression is mediated through distinct transcriptional pathways, modulating cellular responses to retinoids. Additionally, 9-cis-Retinoic acid's lipophilic nature enhances its membrane permeability, promoting efficient cellular uptake. | ||||||
SR 11237 | 146670-40-8 | sc-296418 sc-296418A | 5 mg 50 mg | $211.00 $877.00 | ||
SR 11237 acts as a selective retinoid X receptor (RXR) modulator, exhibiting unique binding dynamics that promote the formation of stable RXR heterodimers. Its structural features enable specific electrostatic interactions and conformational adaptability, enhancing receptor affinity. The compound influences transcriptional activity through distinct signaling cascades, impacting gene regulation. Furthermore, SR 11237's hydrophobic characteristics facilitate its interaction with lipid membranes, optimizing cellular localization and activity. | ||||||
Bexarotene-13C4 | 1185030-01-6 | sc-217754 | 1 mg | $430.00 | ||
Bexarotene-13C4 functions as a selective retinoid X receptor (RXR) modulator, characterized by its isotopic labeling that allows for precise tracking in metabolic studies. Its unique carbon isotope composition alters reaction kinetics, providing insights into molecular interactions. The compound's ability to stabilize RXR heterodimers is enhanced by specific hydrophobic interactions, promoting effective signal transduction pathways. Additionally, its distinct conformational flexibility aids in optimizing receptor engagement and downstream effects. | ||||||
Docosahexaenoic acid-d5 | 1197205-71-2 | sc-218259 sc-218259A sc-218259B | 50 µg 100 µg 1 mg | $139.00 $223.00 $889.00 | 3 | |
Docosahexaenoic acid-d5 serves as a potent retinoid X receptor (RXR) modulator, distinguished by its deuterated structure, which facilitates advanced tracing in biochemical assays. This isotopic variant influences molecular dynamics, enhancing binding affinity through unique hydrogen bonding patterns. Its role in lipid metabolism is underscored by its capacity to interact with membrane proteins, potentially altering cellular signaling cascades. The compound's hydrophilic and hydrophobic balance contributes to its versatile behavior in lipid bilayers, impacting receptor activation and downstream regulatory mechanisms. | ||||||