Date published: 2025-12-6

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RIP Inhibitors

Santa Cruz Biotechnology now offers a broad range of RNA Polymerase Inhibitors for use in various applications. RNA Polymerase Inhibitors are a crucial category of compounds in molecular biology and biochemical research, primarily utilized to study the mechanisms of gene expression and transcriptional regulation. By inhibiting RNA polymerase enzymes, these inhibitors allow researchers to dissect the complex processes of RNA synthesis, providing insights into the transcriptional machinery and its regulation. They are particularly valuable in experiments aiming to understand transcriptional control, gene silencing, and the interactions between RNA polymerase and DNA or other transcription factors. Additionally, RNA Polymerase Inhibitors are essential tools in the study of cellular responses to stress, environmental changes, and various regulatory mechanisms. Their applications extend to the analysis of transcriptional dynamics, the investigation of regulatory pathways, and the exploration of genetic and epigenetic modifications. View detailed information on our available RNA Polymerase Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Necrostatin-1

4311-88-0sc-200142
sc-200142A
20 mg
100 mg
$92.00
$336.00
97
(3)

Necrostatin-1 (CAS 4311-88-0) is a selective inhibitor of receptor-interacting protein kinase 1 (RIP1 or RIPK1), effectively blocking necroptosis, a programmed form of cell death distinct from apoptosis. This compound operates by targeting the kinase activity of RIP1, allowing researchers to study necroptotic pathways in cellular and molecular biology experiments.

DAF-FM DA (cell permeable)

254109-22-3sc-205940
1 mg
$745.00
7
(1)

DAF-FM DA (CAS 254109-22-3) is a cell-permeable chemical probe that inhibits receptor-interacting protein (RIP) kinases. Its properties allow it to permeate cellular membranes, where it serves as a fluorescent dye sensitive to nitric oxide (NO). Upon entry, DAF-FM DA is deacetylated, yielding DAF-FM, which reacts with NO to form a highly fluorescent compound. This makes it valuable in biochemical studies to track and visualize NO-related cellular responses and RIP kinase inhibition dynamics in various biological systems.