| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Necrostatin-1 | 4311-88-0 | sc-200142 sc-200142A | 20 mg 100 mg | $92.00 $336.00 | 97 | |
Necrostatin-1 (CAS 4311-88-0) is a selective inhibitor of receptor-interacting protein kinase 1 (RIP1 or RIPK1), effectively blocking necroptosis, a programmed form of cell death distinct from apoptosis. This compound operates by targeting the kinase activity of RIP1, allowing researchers to study necroptotic pathways in cellular and molecular biology experiments. | ||||||
DAF-FM DA (cell permeable) | 254109-22-3 | sc-205940 | 1 mg | $745.00 | 7 | |
DAF-FM DA (CAS 254109-22-3) is a cell-permeable chemical probe that inhibits receptor-interacting protein (RIP) kinases. Its properties allow it to permeate cellular membranes, where it serves as a fluorescent dye sensitive to nitric oxide (NO). Upon entry, DAF-FM DA is deacetylated, yielding DAF-FM, which reacts with NO to form a highly fluorescent compound. This makes it valuable in biochemical studies to track and visualize NO-related cellular responses and RIP kinase inhibition dynamics in various biological systems. | ||||||