Date published: 2026-5-2

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Ribosomal Protein S13 Inhibitors

Ribosomal Protein S13 Inhibitors are a class of chemical compounds that primarily target a specific component of the ribosome, the cellular machinery responsible for protein synthesis. These inhibitors interfere with the functioning of Ribosomal Protein S13, a crucial structural protein within the small subunit of the ribosome. Ribosomal Protein S13 is essential for the assembly and stability of the small ribosomal subunit, which plays a pivotal role in decoding the genetic information carried by mRNA (messenger RNA) and catalyzing the synthesis of proteins in all living organisms. Inhibiting Ribosomal Protein S13 disrupts this fundamental biological process, resulting in significant consequences for cellular protein production.

Ribosomal Protein S13 Inhibitors involves binding to the target protein and disrupting its interaction with other ribosomal components, as well as with the mRNA. This interference ultimately hinders the ribosome's ability to accurately decode mRNA sequences and synthesize proteins. As a consequence, the translation process becomes compromised, leading to reduced or aberrant protein synthesis. The specific structural and biochemical features of Ribosomal Protein S13 that these inhibitors exploit for their inhibitory effects make them a valuable tool in research settings, where they are used to dissect the intricacies of ribosome function and study the mechanisms underlying protein synthesis. Their significance in understanding fundamental cellular processes highlights the importance of Ribosomal Protein S13 Inhibitors in molecular biology and structural biology research.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

α-Sarcin

86243-64-3sc-204427
1 mg
$462.00
6
(0)

Cleaves a single phosphodiester bond within the ribosomal RNA of the large ribosomal subunit, leading to inhibition of protein synthesis.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Binds to the 60S ribosomal subunit and inhibits peptidyl transferase activity, thereby blocking protein synthesis.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis by interfering with the translocation step in protein synthesis, thus blocking translational elongation.

Chloramphenicol

56-75-7sc-3594
25 g
$90.00
10
(1)

Binds to the 50S ribosomal subunit and inhibits bacterial protein synthesis by blocking peptidyl transferase activity.

Tetracycline

60-54-8sc-205858
sc-205858A
sc-205858B
sc-205858C
sc-205858D
10 g
25 g
100 g
500 g
1 kg
$63.00
$94.00
$270.00
$417.00
$634.00
6
(1)

Binds to the 30S ribosomal subunit and inhibits protein synthesis by blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site.

Erythromycin

114-07-8sc-204742
sc-204742A
sc-204742B
sc-204742C
5 g
25 g
100 g
1 kg
$57.00
$245.00
$831.00
$1331.00
4
(3)

Binds to the 50S ribosomal subunit and inhibits translocation of the peptidyl-tRNA from the A-site to the P-site on the ribosome.

Fusidic acid

6990-06-3sc-215065
1 g
$292.00
(0)

Binds to elongation factor G (EF-G) on the ribosome and prevents the release of EF-G from the GDP-bound ribosome, stalling protein synthesis.

Gentamicin Sulfate, 500X Solution

1405-41-0sc-29066A
sc-29066
sc-29066B
10 ml
20 ml
100 ml
$48.00
$85.00
$115.00
12
(1)

Bind to the 30S ribosomal subunit and cause misreading of mRNA, leading to the synthesis of nonfunctional proteins.