Date published: 2025-10-25

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RGPD5 Inhibitors

The chemical class termed RGPD5 Inhibitors represents a group of compounds specifically designed to selectively target the molecular entity RGPD5. The RGPD5 gene encodes a member of the RANBP2 family, which is involved in nucleocytoplasmic transport and the regulation of gene expression. Despite the crucial cellular functions associated with RGPD5, its precise roles and interactions are still under active investigation. Inhibitors within this chemical class are intricately engineered molecules with the primary aim of modulating the activity or function of RGPD5, thereby exerting an inhibitory effect. Researchers exploring RGPD5 Inhibitors utilize a comprehensive approach, integrating insights from structural biology, medicinal chemistry, and computational methods to unravel the intricate molecular interactions between the inhibitors and the target RGPD5.

Structurally, RGPD5 Inhibitors are characterized by their specific molecular features designed to facilitate selective binding to RGPD5. This selectivity is essential to minimize off-target effects on other cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves an exhaustive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with RGPD5. As researchers delve deeper into the functional aspects of RGPD5 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of RGPD5 but also to advancing our broader understanding of cellular processes and molecular regulation. The exploration of RGPD5 Inhibitors stands as a significant avenue for expanding fundamental knowledge in molecular pharmacology and cellular biology.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

This antibiotic intercalates into DNA, preventing RNA polymerase from continuing transcription, which could nonspecifically reduce RGPD5 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

As a diterpene triepoxide, triptolide has been shown to inhibit RNA polymerase II, which could reduce the transcription of a wide range of genes including RGPD5.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

α-Amanitin targets RNA polymerase II and III, inhibiting mRNA synthesis which might lead to decreased expression of genes such as RGPD5.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

By terminating mRNA elongation, cordycepin could potentially reduce the levels of many mRNAs, possibly including that of RGPD5.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

DRB selectively inhibits RNA polymerase II transcriptional elongation, which could result in reduced expression of genes, potentially including RGPD5.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

This compound inhibits eukaryotic protein synthesis, which could indirectly decrease RGPD5 levels by preventing its translation.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

Puromycin causes premature termination during protein synthesis, which could nonspecifically decrease the synthesis of many proteins, including RGPD5.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Flavopiridol is a cyclin-dependent kinase inhibitor that can affect transcription regulation, potentially decreasing RGPD5 gene expression.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$226.00
$846.00
1
(0)

By inhibiting BET bromodomains, JQ1 can alter chromatin accessibility and gene transcription, potentially affecting RGPD5 expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

As an HDAC inhibitor, trichostatin A could lead to changes in chromatin structure and gene expression, possibly including RGPD5.