RAP1 Inhibitors
RAP1 inhibitors are a class of small molecules or compounds that specifically target and inhibit the function of RAP1 (Repressor Activator Protein 1), a crucial regulatory protein involved in various cellular processes. RAP1 itself belongs to the Ras superfamily of small GTPases and plays a pivotal role in the regulation of gene expression, cell proliferation, differentiation, and cell adhesion. These inhibitors are designed to disrupt the normal activity of RAP1 within cells, and as a result, they have garnered significant attention in both basic research and compound development due to their potential impact on various cellular functions.
The mechanism of action of RAP1 inhibitors typically involves interfering with the activation or signaling pathways of RAP1. This can be achieved by directly binding to RAP1 or its associated proteins, preventing its activation by GTP, or disrupting its downstream interactions with effectors. By inhibiting RAP1, these compounds influences cellular processes such as cell adhesion, migration, and differentiation, which are essential for normal tissue development and maintenance. Additionally, RAP1 inhibitors may have implications in the context of research, as abnormal RAP1 activity has been linked to metastasis. Furthermore, the study of RAP1 inhibitors can shed light on the intricate signaling networks that govern cellular behavior and contribute to a deeper understanding of cell biology and disease mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol, a flavonoid found in various fruits and vegetables, has demonstrated potential in inhibiting RAP1 expression. Its effects are thought to be mediated through its antioxidant properties and its ability to modulate cellular signaling pathways, potentially affecting cell proliferation and survival. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein, a flavone found in the roots of Scutellaria baicalensis, has been observed to downregulate RAP1 expression. Its inhibitory effects may be associated with its anti-inflammatory and antioxidant properties, potentially modulating various cellular pathways. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin, a flavonoid present in many fruits and vegetables, has potential inhibitory effects on RAP1 expression. Its action may be related to its antioxidant and anti-inflammatory properties, which could affect signaling pathways involved in cell survival and proliferation. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid, found in berries and pomegranates, has demonstrated potential to inhibit RAP1 expression. Its effects are thought to be related to its antioxidant properties and its ability to influence cellular aging and survival pathways. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin, a flavonoid found in various fruits and vegetables, has been shown to potentially downregulate RAP1 expression. Its inhibitory effects are believed to be mediated through its antioxidant properties and its influence on cellular signaling pathways. | ||||||
Pterostilbene, Pterocarpus marsupium | 537-42-8 | sc-203223 sc-203223A | 10 mg 100 mg | $211.00 $1196.00 | ||
Pterostilbene, a stilbenoid chemically related to resveratrol, has potential inhibitory effects on RAP1 expression. Its action is thought to be linked to its antioxidant properties and its ability to modulate various signaling pathways, potentially affecting cellular aging and survival. | ||||||
Oleuropein | 32619-42-4 | sc-286622 sc-286622A sc-286622B sc-286622C | 500 mg 1 g 10 g 100 g | $359.00 $530.00 $791.00 $6773.00 | 2 | |
Oleuropein, a compound found in olive leaves, has demonstrated potential in inhibiting RAP1 expression. Its effects may be associated with its antioxidant and anti-inflammatory properties, potentially modulating cellular responses to stress and aging. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
Honokiol, a lignan isolated from the bark, seed cones, and leaves of trees belonging to the genus Magnolia, has potential inhibitory effects on RAP1 expression. Its action is believed to be linked to its anti-inflammatory and antioxidant properties, potentially affecting cellular signaling pathways. | ||||||
Xanthohumol from hop (Humulus lupulus) | 6754-58-1 | sc-301982 | 5 mg | $361.00 | 1 | |
Xanthohumol, a prenylated chalcone found in hops, has been observed to inhibit RAP1 expression. Its effects are thought to be related to its antioxidant properties and its ability to modulate cellular signaling pathways, potentially affecting cell proliferation and survival. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $40.00 | 7 | |
Andrographolide, a labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata, has potential inhibitory effects on RAP1 expression. Its action is believed to be associated with its anti-inflammatory properties, potentially modulating cellular responses to stress and inflammation. | ||||||