RAET1G inhibitors belong to a class of chemical compounds designed to selectively target and modulate the activity of the RAET1G protein. RAET1G, also known as retinoic acid early transcript 1G, is a transmembrane protein that plays a crucial role in immune regulation. It is primarily expressed on the surface of certain cells, particularly those involved in the immune response, such as dendritic cells and activated T cells. The RAET1G protein is recognized for its ability to interact with natural killer (NK) cells and regulate their activity. NK cells are integral components of the innate immune system, responsible for detecting and eliminating abnormal cells, including infected or cancerous cells.
Inhibitors targeting RAET1G function by binding to specific sites on the protein, thereby modulating its activity and subsequent interactions with NK cells. By manipulating the RAET1G pathway, these inhibitors aim to influence the immune response and cellular recognition processes. The rational design of RAET1G inhibitors involves a detailed understanding of the protein's structure and its role in immune signaling. Researchers in the field of immunopharmacology are actively exploring the potential of RAET1G inhibitors as tools to elucidate immune system functions and unravel the intricate dynamics of cellular communication. The development of such inhibitors contributes to advancing our knowledge of immune responses.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a proteasome inhibitor that can alter cellular signaling and transcription factor activity, potentially impacting RAET1G expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation and can induce ER stress, which could affect the expression of proteins like RAET1G. |