RADIL inhibitors refer to a class of chemical compounds that are primarily designed to target and modulate the activity of the RADIL protein. RADIL, also known as Rap GTPase-GDP dissociation inhibitor-like 1, is a cytoplasmic protein that plays a significant role in cellular signaling and cytoskeletal dynamics. These inhibitors are molecular tools used in laboratory research to investigate the specific functions and interactions of RADIL within the cell, shedding light on its involvement in various cellular processes.
RADIL itself is a multifunctional protein involved in cell adhesion, migration, and signaling pathways. It is associated with the regulation of RAP GTPases, which are key players in controlling the actin cytoskeleton and cell adhesion dynamics. RADIL inhibitors are designed to interfere with the normal function of RADIL by binding to it or disrupting its interactions with other cellular components. This interference can help researchers dissect the precise role of RADIL in different cellular processes and gain insights into its downstream effects.Researchers often use RADIL inhibitors in conjunction with other experimental techniques, such as genetic manipulations or biochemical assays, to elucidate the intricate mechanisms by which RADIL influences cell behavior. By selectively inhibiting RADIL's function, researchers can explore its impact on cellular processes like cell motility, adhesion, and intracellular signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Amifostine | 20537-88-6 | sc-200937 sc-200937A | 10 mg 50 mg | $79.00 $311.00 | 6 | |
Acts as a prodrug, scavenging free radicals to reduce DNA damage and enhance the cellular antioxidant defense system. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Acts as a radical scavenger and can reduce the toxicity of radiation-induced free radicals in cells. | ||||||
Ebselen | 60940-34-3 | sc-200740B sc-200740 sc-200740A | 1 mg 25 mg 100 mg | $33.00 $136.00 $458.00 | 5 | |
Acts as a glutathione peroxidase mimic, reducing oxidative damage caused by radiation by catalyzing the reduction of peroxides. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Induces DNA cross-linking, blocking DNA replication and inhibit in rapidly dividing cells exposed to radiation. | ||||||
Pentoxifylline | 6493-05-6 | sc-203184 | 1 g | $20.00 | 3 | |
Reduces radiation-induced inflammation and fibrosis by inhibiting cytokine release and improving tissue oxygenation. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $65.00 $73.00 $218.00 $697.00 $1196.00 $3574.00 | 16 | |
Scavenges free radicals, regulates circadian rhythms, and may inhibit against radiation-induced oxidative stress. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Inhibits topoisomerase II, inhibiting DNA strand breaks, and may enhance the radiation sensitivity of cancer cells. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $208.00 | ||
Acts as a radioprotectant by reducing inflammation, improving tissue hydration, and enhancing wound healing post-radiation. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Enhances radiation sensitivity by inhibiting DNA repair processes and increasing the likelihood of cell death after exposure. | ||||||