The RAD30 protein, encoded by the RAD30 gene in humans, is a vital component in DNA repair mechanisms, specifically in translesion synthesis. This critical process allows the DNA replication machinery to bypass DNA lesions that are triggered by environmental factors and internal cellular activities. RAD30 plays a crucial role in replicating past UV-induced DNA damage, thereby mitigating the risk of genetic mutations that could potentially disrupt normal cell function and growth. This protein's role in maintaining the integrity of the genetic code makes it a crucial focus of scientific study, especially in the areas of molecular biology and genetics.
Several chemical compounds, found naturally in our environment, have been hypothesized to potentially induce the expression of the RAD30 protein. For example, Resveratrol, a polyphenolic compound found in grapes and red wine, and Curcumin, a natural compound found in turmeric, may both elevate RAD30 expression due to their ability to induce DNA damage response pathways, including translesion synthesis. Similarly, Genistein, a soy isoflavone, might enhance RAD30 expression through its interaction with estrogen receptors, which subsequently activate DNA repair pathways. Other compounds such as Sulforaphane, found in cruciferous vegetables, and Quercetin, a flavonoid present in many fruits and vegetables, might stimulate RAD30 expression as part of the cellular response to oxidative stress. Such compounds highlight the complex interplay between our diet, cellular mechanisms, and genetic integrity. However, it is important to note that these are theoretical interactions, and further scientific research is necessary to confirm these potential relationships with RAD30.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenolic compound found in grapes and red wine, may upregulate RAD30 expression due to its ability to induce DNA damage response pathways, which include translesion synthesis. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a natural compound found in turmeric. It can cause mild DNA damage, potentially leading to increased expression of RAD30 as part of the DNA damage response. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a soy isoflavone, may enhance RAD30 expression through its ability to interact with estrogen receptors and subsequently activate DNA repair pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane, a compound found in cruciferous vegetables like broccoli, may boost RAD30 expression due to its capability to induce cellular stress response pathways, including DNA repair mechanisms. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid present in many fruits and vegetables, may stimulate RAD30 expression as part of the cellular response to its pro-oxidant effects, which can induce minor DNA damage. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate (EGCG), a compound in green tea, may induce RAD30 expression due to its potential to cause mild DNA damage and stimulate DNA repair machinery. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid, present in several fruits and nuts, may induce RAD30 expression by causing minor DNA damage and subsequently stimulating the DNA damage response. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin, the active compound in chili peppers, may stimulate RAD30 expression as part of the cell's response to its pro-oxidant effects, which can lead to mild DNA damage. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $143.00 $571.00 $6125.00 | 4 | |
Lycopene, a carotenoid found in tomatoes, may potentially induce RAD30 expression as part of the cell's response to oxidative stress, thereby enhancing DNA repair mechanisms. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, may boost RAD30 expression by modulating gene expression patterns, including those involved in DNA repair pathways. | ||||||