Rac Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Toxin A from Clostridium difficile | sc-222361 sc-222361A | 2 µg 100 µg | $192.00 $772.00 | |||
Toxin A from Clostridium difficile is a potent glucosyltransferase that modifies Rho GTPases, disrupting cellular signaling pathways. Its enzymatic activity leads to actin cytoskeleton disassembly, promoting cell rounding and apoptosis. The toxin's specificity for certain Rho family proteins highlights its unique interaction dynamics. Additionally, Toxin A's ability to induce inflammatory responses showcases its role in altering host immune mechanisms, further complicating cellular responses. | ||||||
EHT 1864 | 754240-09-0 | sc-361175 sc-361175A | 10 mg 50 mg | $209.00 $872.00 | 12 | |
EHT 1864 acts as a potent Rac inhibitor, selectively modulating the activity of Rho family GTPases. Its unique binding affinity allows it to disrupt the nucleotide exchange process, effectively altering downstream signaling cascades. The compound exhibits distinct kinetic properties, facilitating rapid inhibition of Rac-mediated pathways. This selective interaction leads to significant changes in cellular dynamics, influencing processes such as migration and adhesion through targeted molecular interference. | ||||||
Ras/Rac Transformation Blocker, SCH 51344 | 171927-40-5 | sc-204231 | 10 mg | $146.00 | 4 | |
SCH 51344 serves as a specialized Ras/Rac transformation blocker, exhibiting a unique mechanism of action through its interaction with GTPase proteins. By stabilizing the inactive form of Rac, it effectively impedes the nucleotide exchange process, leading to altered cellular signaling. Its distinct kinetic profile allows for swift modulation of Rac activity, impacting various cellular functions, including cytoskeletal organization and cellular morphology, through precise molecular engagement. | ||||||