Potassium Channel Modulators
Items 71 to 80 of 103 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ZM 226600 | 147695-92-9 | sc-281189 sc-281189A | 10 mg 50 mg | $100.00 $348.00 | ||
ZM 226600 functions as a potassium channel modulator by selectively binding to distinct allosteric sites on the channel protein, inducing unique conformational shifts that enhance or inhibit ion flow. Its intricate molecular architecture allows for targeted interactions with specific potassium channel isoforms, thereby fine-tuning their gating dynamics. This modulation can significantly influence cellular excitability and signal transduction pathways, showcasing its nuanced role in ion channel behavior. | ||||||
NS-1619 | 153587-01-0 | sc-200986 | 5 mg | $130.00 | 2 | |
NS-1619 acts as a potassium channel modulator by engaging with specific binding sites on the channel, leading to alterations in ion permeability. Its unique structural features facilitate interactions that stabilize certain channel conformations, impacting the kinetics of ion transport. This compound exhibits a selective affinity for various potassium channel subtypes, allowing for precise modulation of electrical signaling in cells, thereby influencing overall cellular function and responsiveness. | ||||||
LY 303511 | 154447-38-8 | sc-202215 sc-202215A | 1 mg 5 mg | $66.00 $273.00 | 3 | |
LY 303511 functions as a potassium channel modulator by selectively interacting with the channel's voltage-sensing domains, which influences gating mechanisms. Its unique molecular architecture promotes distinct conformational changes, enhancing or inhibiting ion flow. The compound demonstrates varied kinetics across different potassium channel isoforms, allowing for nuanced regulation of cellular excitability and ion homeostasis, ultimately affecting cellular signaling pathways. | ||||||
Chromanol 293B | 163163-23-3 | sc-203889 sc-203889A | 10 mg 50 mg | $178.00 $759.00 | 1 | |
Chromanol 293B acts as a potassium channel modulator by engaging with specific binding sites on the channel protein, leading to alterations in ion permeability. Its structural features facilitate unique interactions with lipid bilayers, influencing channel dynamics and stability. The compound exhibits differential effects on various potassium channel subtypes, resulting in tailored modulation of electrical activity and ion transport, thereby impacting cellular membrane potential and excitability. | ||||||
UCL-1848 trifluoroacetate salt | 201147-53-7 | sc-253819 sc-253819A | 5 mg 25 mg | $154.00 $510.00 | ||
UCL-1848 trifluoroacetate salt functions as a potassium channel modulator by selectively interacting with the channel's voltage-sensing domains, which enhances its gating properties. Its trifluoroacetate moiety contributes to hydrophobic interactions, promoting stability within lipid environments. This compound exhibits rapid kinetics in channel activation and inactivation, allowing for precise control over ion flow and influencing cellular signaling pathways through modulation of membrane potential. | ||||||
CP-339818 | 478341-55-8 | sc-252641 | 5 mg | $62.00 | ||
CP-339818 functions as a potassium channel modulator by selectively binding to the channel's regulatory sites, influencing its gating mechanisms. This compound exhibits unique allosteric modulation, which alters the channel's ion selectivity and permeability. Its kinetic profile reveals a rapid onset of action, promoting immediate changes in membrane potential. Additionally, CP-339818's hydrophobic characteristics enhance its affinity for lipid environments, optimizing its interaction with cellular membranes. | ||||||
GW 542573X | 660846-41-3 | sc-362741 sc-362741A | 10 mg 50 mg | $175.00 $739.00 | ||
GW 542573X acts as a potassium channel modulator through its ability to interact with specific binding domains on the channel protein, leading to alterations in ion flow dynamics. This compound demonstrates a unique capacity for stabilizing the open state of the channel, thereby enhancing ion conductance. Its structural features promote effective integration into lipid bilayers, facilitating rapid channel activation and influencing downstream signaling pathways. The compound's selective interaction profile underscores its potential for fine-tuning cellular excitability. | ||||||
Psora-4 | 724709-68-6 | sc-253325 | 5 mg | $196.00 | ||
Psora-4 functions as a potassium channel modulator by selectively binding to allosteric sites on the channel, resulting in nuanced alterations in gating kinetics. Its unique molecular architecture allows for enhanced affinity towards specific channel subtypes, promoting differential ion permeability. The compound exhibits a remarkable ability to influence channel desensitization rates, thereby modulating cellular excitability and signal transduction with precision. Its interactions with membrane lipids further optimize channel responsiveness. | ||||||
5-(4-Phenoxybutoxy)psoralen | 870653-45-5 | sc-252247 sc-252247A | 5 mg 25 mg | $116.00 $714.00 | 1 | |
5-(4-Phenoxybutoxy)psoralen acts as a potassium channel modulator through its distinctive ability to interact with the channel's lipid bilayer environment, enhancing channel stability and function. This compound exhibits a unique binding profile that influences the conformational dynamics of the channel, leading to altered ion flow and channel activation thresholds. Its structural features facilitate specific interactions with channel proteins, promoting selective modulation of electrical signaling pathways. | ||||||
UCL 2077 | 918311-87-2 | sc-204371 sc-204371A | 10 mg 50 mg | $135.00 $575.00 | ||
UCL 2077 functions as a potassium channel modulator by uniquely engaging with the channel's pore region, altering ion selectivity and permeability. Its molecular structure allows for specific hydrogen bonding and hydrophobic interactions with amino acid residues, which fine-tune the channel's gating mechanisms. This compound exhibits rapid kinetics in channel activation and inactivation, providing a nuanced control over ionic currents and contributing to the modulation of cellular excitability. | ||||||