PKAβ cat (Protein Kinase A beta catalytic subunit) activators pertain to a class of compounds or molecules that are designed to modulate the activity of PKAβ catalytic subunit. PKAβ is one of the two catalytic subunits (the other being PKAα) that, along with regulatory subunits, constitute the cAMP-dependent protein kinase (PKA) enzyme. PKA is a critical component of many intracellular signaling pathways. It plays a fundamental role in the phosphorylation of target proteins in response to elevated levels of cyclic AMP (cAMP), thereby transducing extracellular signals into cellular responses. Activators of PKAβ cat are molecules that enhance the catalytic activity of this subunit, possibly by stabilizing its conformation or promoting its binding to ATP, which is necessary for kinase activity.
The study of PKAβ cat activators is crucial for understanding the intricacies of cellular signaling and phosphorylation cascades. PKA itself regulates a plethora of cellular processes, including metabolism, gene expression, and cell proliferation. By specifically targeting the catalytic subunit, these activators can provide valuable insights into the role of PKAβ in various cellular contexts. Nevertheless, it's important to conduct further research to precisely characterize these activators and their implications for modulating PKAβ cat activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Directly stimulates adenylyl cyclase, increasing cAMP levels and potentially influencing PKA expression or activation. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
A beta-adrenergic agonist that can increase cAMP levels, potentially modulating PKA. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Acts on adrenergic receptors, leading to increased cAMP and potential effects on PKA. | ||||||
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
A membrane-permeable analog of cAMP that can activate PKA. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $31.00 $145.00 | 16 | |
Can increase cAMP levels in certain cell types, potentially influencing PKA. | ||||||
Calcitonin, Salmon | 47931-85-1 | sc-201167 sc-201167A | 1 mg 5 mg | $154.00 $625.00 | 1 | |
Acts via its receptor to increase cAMP in certain contexts, potentially influencing PKA. | ||||||