PIP5KII Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY 294002 could downregulate PIP5KII expression by inhibiting PI3K, leading to attenuated AKT signaling and consequent decrease in the transcriptional activation of PIP5KII gene expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin may suppress PIP5KII expression through the inhibition of PI3K, which would result in diminished AKT phosphorylation and potentially lower the translation of PIP5KII mRNA. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 could decrease PIP5KII expression by specifically inhibiting MEK1/2, leading to reduced ERK pathway activity, which may be necessary for the transcriptional activation of the PIP5KII gene. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin might lead to a decrease in PIP5KII synthesis by inhibiting mTOR, a crucial kinase for protein synthesis, which could result in a reduced abundance of PIP5KII enzyme. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB 203580 potentially reduces PIP5KII expression by selectively inhibiting p38 MAPK, which may play a role in the transcriptional machinery for the PIP5KII gene. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 may lead to reduced expression of PIP5KII by selectively inhibiting JNK, thereby potentially decreasing the activity of transcription factors that promote PIP5KII gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein could downregulate PIP5KII expression by inhibiting specific tyrosine kinases that are upstream of transcription factors which drive the expression of the PIP5KII gene. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Triciribine might reduce PIP5KII expression by directly inhibiting AKT, which is implicated in the signal transduction pathways that govern the translation efficiency and stability of PIP5KII mRNA. | ||||||
Chelerythrine | 34316-15-9 | sc-507380 | 100 mg | $540.00 | ||
Chelerythrine could lead to a decrease in PIP5KII expression by inhibiting PKC, which may alter specific phosphorylation events on transcription factors involved in the transcription of the PIP5KII gene. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Gö 6983 might suppress the expression of PIP5KII by inhibiting several isoforms of PKC, potentially leading to decreased activation of transcription factors essential for PIP5KII gene transcription. | ||||||