Items 21 to 23 of 23 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Compound 15e | 371943-05-4 | sc-202551 sc-202551A | 1 mg 5 mg | $51.00 $206.00 | ||
Compound 15e is a selective inhibitor of the p110 gamma isoform of PI3-kinase, characterized by its unique molecular interactions that promote a conformational shift in the enzyme. This compound effectively alters the enzyme's affinity for phosphoinositides, leading to a significant reduction in lipid phosphorylation. Its reaction kinetics suggest a competitive inhibition model, impacting the enzyme's catalytic efficiency and influencing cellular signaling dynamics. | ||||||
PIK-293 | 900185-01-5 | sc-364585 sc-364585A | 5 mg 50 mg | $370.00 $1950.00 | ||
PIK-293 is a highly selective inhibitor targeting the p110 gamma isoform of PI3-kinase, distinguished by its ability to disrupt key protein-lipid interactions. This compound induces a notable alteration in the enzyme's active site, which affects substrate binding and alters downstream signaling pathways. Its kinetic profile indicates a non-competitive inhibition mechanism, thereby modulating the enzyme's activity without directly competing with the substrate, ultimately influencing cellular responses. | ||||||
PIK-75, free base | 372196-67-3 | sc-394297 | 5 mg | $83.00 | 1 | |
PIK-75, free base, is a selective inhibitor of the p110 gamma isoform of PI3-kinase, characterized by its unique ability to stabilize the inactive conformation of the enzyme. This stabilization disrupts critical protein-protein interactions, leading to a significant reduction in lipid phosphorylation. The compound exhibits a distinct allosteric modulation, influencing the enzyme's conformational dynamics and altering its catalytic efficiency, thereby impacting various cellular signaling cascades. | ||||||