PGF2alphaR Activators
SEE ALSO...
Items 1 to 10 of 24 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PGF2α (Prostaglandin F2α) | 38562-01-5 | sc-201227 sc-201227B sc-201227A sc-201227C | 1 mg 5 mg 10 mg 25 mg | $42.00 $168.00 $300.00 $664.00 | 5 | |
PGF2α acts as a potent ligand for the PGF2α receptor, initiating a cascade of intracellular signaling pathways. Its unique stereochemistry allows for specific interactions with receptor binding sites, promoting conformational changes that activate G-proteins. This interaction triggers downstream effects, including modulation of calcium ion flux and activation of phospholipase C. The compound's hydrophilic nature enhances its solubility in aqueous environments, facilitating rapid receptor engagement and signal transduction. | ||||||
(+)-Cloprostenol (sodium salt) | 62561-03-9 | sc-205260 sc-205260A | 1 mg 5 mg | $98.00 $443.00 | ||
(+)-Cloprostenol (sodium salt) exhibits remarkable affinity for the PGF2α receptor, characterized by its ability to stabilize receptor conformations that enhance G-protein coupling efficiency. The compound's unique stereochemical configuration facilitates selective binding, leading to distinct activation of intracellular pathways. Its ionic nature contributes to increased solubility, promoting swift interactions with membrane-bound receptors and influencing downstream signaling cascades, including the modulation of cyclic AMP levels. | ||||||
Prostaglandin F2α | 551-11-1 | sc-203219 | 1 mg | $88.00 | 1 | |
Dinoprost is a synthetic form of prostaglandin F2α that can directly bind and activate PGF2αR. | ||||||
Prostaglandin F2α-d4 | 34210-11-2 | sc-205468 sc-205468A | 50 µg 100 µg | $51.00 $130.00 | ||
Prostaglandin F2α-d4 is a stable isotopologue that selectively engages the PGF2α receptor, promoting unique conformational changes that optimize receptor activation. Its deuterated structure enhances metabolic stability, allowing for prolonged interaction with G-proteins. This compound's distinct kinetic profile facilitates rapid receptor binding and subsequent activation of signaling pathways, influencing various cellular responses. Its isotopic labeling also aids in tracking metabolic pathways in research applications. | ||||||
Tafluprost (free acid) | 209860-88-8 | sc-205516 sc-205516A | 1 mg 5 mg | $140.00 $630.00 | ||
Tafluprost (free acid) is a potent agonist of the PGF2α receptor, characterized by its ability to induce specific conformational shifts that enhance receptor affinity. Its unique structural features facilitate selective binding, leading to distinct downstream signaling cascades. The compound exhibits a favorable interaction with G-proteins, promoting efficient signal transduction. Additionally, its stability under physiological conditions allows for sustained receptor engagement, influencing cellular dynamics effectively. | ||||||
(+)-Cloprostenol | 54276-21-0 | sc-205259 sc-205259A | 1 mg 5 mg | $75.00 $453.00 | ||
(+)-Cloprostenol acts as a selective agonist for the PGF2α receptor, showcasing a unique ability to stabilize receptor conformations that promote enhanced signaling efficacy. Its molecular design allows for specific hydrogen bonding interactions, which fine-tune receptor activation. The compound's kinetic profile reveals rapid binding and dissociation rates, facilitating dynamic modulation of intracellular pathways. Furthermore, its lipophilic nature aids in membrane permeability, influencing bioavailability and receptor interaction. | ||||||
Cloprostenol Sodium | 55028-72-3 | sc-201338 sc-201338A | 1 mg 10 mg | $73.00 $217.00 | ||
Cloprostenol Sodium is a potent agonist of the PGF2α receptor, characterized by its ability to induce specific conformational changes that enhance receptor activation. The compound exhibits unique electrostatic interactions that facilitate its binding affinity, promoting effective signal transduction. Its rapid kinetics enable swift receptor engagement, while its amphipathic properties enhance its interaction with lipid membranes, optimizing cellular uptake and subsequent biological responses. | ||||||
Fluprostenol | 40666-16-8 | sc-201336 sc-201336A | 1 mg 10 mg | $62.00 $510.00 | ||
Fluprostenol acts as a selective agonist for the PGF2α receptor, showcasing a unique ability to stabilize receptor conformations that trigger downstream signaling cascades. Its structural features allow for specific hydrogen bonding and hydrophobic interactions, enhancing binding specificity. The compound's dynamic behavior in solution contributes to its effective diffusion across cellular membranes, facilitating rapid receptor activation and subsequent physiological effects. | ||||||
Latanoprost (free acid) | 41639-83-2 | sc-205364 sc-205364A sc-205364A-CW | 1 mg 5 mg 5 mg | $122.00 $422.00 $600.00 | ||
Latanoprost (free acid) exhibits a remarkable affinity for the PGF2α receptor, characterized by its ability to induce conformational changes that enhance receptor activation. The compound's unique stereochemistry facilitates specific interactions with receptor binding sites, promoting effective signal transduction. Its solubility properties enable efficient cellular uptake, while its kinetic profile suggests rapid receptor engagement, leading to pronounced biological responses. The compound's structural flexibility further contributes to its interaction dynamics within lipid environments. | ||||||
Bimatoprost | 155206-00-1 | sc-205224 sc-205224A | 1 mg 5 mg | $120.00 $464.00 | 1 | |
Bimatoprost is a synthetic prostamide with a structure related to prostaglandin F2α. It activates PGF2αR after being metabolized to bimatoprost acid. | ||||||