The chemical class known as PF4V1 Inhibitors comprises a diverse range of compounds that modulate the activation and function of PF4V1. These chemicals primarily act by inhibiting matrix metalloproteinases (MMPs), which play crucial roles in extracellular matrix remodeling and cellular processes associated with PF4V1. Suramin, SB-3CT, PD-166793, Marimastat, Batimastat, TAPI-1, ARP101, GM6001, Prinomastat, MMI-166, NSC 405020, and ONO-4817 are among the inhibitors that can indirectly impact PF4V1 by interfering with MMP-mediated pathways. Suramin, for instance, is a polysulfonated naphthylurea known for inhibiting growth factors and chemokines. It may indirectly inhibit PF4V1 by disrupting signaling pathways involving these factors, consequently influencing cellular processes linked to PF4V1. Similarly, MMP inhibitors like SB-3CT and PD-166793 can modulate PF4V1 by influencing pathways related to extracellular matrix remodeling, providing avenues for indirect inhibition. The broader spectrum MMP inhibitors, including Marimastat, Batimastat, TAPI-1, ARP101, GM6001, Prinomastat, MMI-166, NSC 405020, and ONO-4817, collectively contribute to a nuanced understanding of pathways for PF4V1 inhibition.
These chemicals offer valuable insights into the intricate relationships between MMPs and PF4V1, emphasizing the interconnected nature of cellular processes involved in PF4V1 modulation. Understanding the specific biochemical and cellular pathways influenced by these inhibitors provides a foundation for designing targeted strategies to modulate PF4V1 within diverse cellular contexts. The complex interplay between MMP inhibition and PF4V1 activation opens avenues for further research into the molecular mechanisms governing PF4V1 function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin is a polysulfonated naphthylurea that inhibits various growth factors and chemokines. It may indirectly inhibit PF4V1 by interfering with signaling pathways involving these factors, potentially impacting cellular processes linked to PF4V1. | ||||||
SB-3CT | 292605-14-2 | sc-205847 sc-205847A | 1 mg 5 mg | $102.00 $388.00 | 15 | |
SB-3CT is a matrix metalloproteinase (MMP) inhibitor that can potentially influence PF4V1. By inhibiting MMPs, it may modulate pathways related to extracellular matrix remodeling, indirectly affecting PF4V1 and its associated cellular functions. | ||||||
PD166793 | 199850-67-4 | sc-202709 | 5 mg | $150.00 | 6 | |
PD-166793 is a matrix metalloproteinase (MMP) inhibitor that may impact PF4V1 indirectly. Through its inhibition of MMPs, it can influence pathways associated with extracellular matrix dynamics, potentially leading to modulation of PF4V1 and its cellular functions. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
Marimastat is a broad-spectrum matrix metalloproteinase (MMP) inhibitor. By targeting MMPs, it can potentially influence PF4V1 through the modulation of pathways related to extracellular matrix remodeling, leading to indirect inhibition of PF4V1 and its associated cellular processes. | ||||||
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $179.00 $377.00 | 24 | |
Batimastat is a matrix metalloproteinase (MMP) inhibitor that may affect PF4V1 indirectly. By inhibiting MMPs, it can modulate pathways associated with extracellular matrix dynamics, potentially leading to the indirect inhibition of PF4V1 and its associated cellular functions. | ||||||
TAPI-1 | 171235-71-5 | sc-222337 | 1 mg | $669.00 | 15 | |
TAPI-1 is a broad-spectrum metalloproteinase inhibitor that may impact PF4V1 indirectly. Through its inhibition of metalloproteinases, it can influence pathways related to extracellular matrix remodeling, potentially leading to modulation of PF4V1 and its cellular functions. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
GM6001 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that may impact PF4V1 indirectly. Through its inhibition of MMPs, it can modulate pathways related to extracellular matrix dynamics, potentially leading to indirect inhibition of PF4V1 and its associated cellular processes. | ||||||
Prinomastat | 192329-42-3 | sc-507449 | 5 mg | $190.00 | ||
Prinomastat is a matrix metalloproteinase (MMP) inhibitor that may influence PF4V1 indirectly. By targeting MMPs, it can modulate pathways associated with extracellular matrix dynamics, potentially leading to the indirect inhibition of PF4V1 and its associated cellular functions. | ||||||
NSC 405020 | 7497-07-6 | sc-477738 | 10 mg | $105.00 | ||
NSC 405020 is a matrix metalloproteinase (MMP) inhibitor that may indirectly influence PF4V1. Through its inhibition of MMPs, it can modulate pathways related to extracellular matrix dynamics, potentially leading to the indirect inhibition of PF4V1 and its associated cellular processes. | ||||||
MMP Inhibitor V | 223472-31-9 | sc-203139 | 2 mg | $220.00 | 2 | |
MMP Inhibitor V (ONO-4817) is a matrix metalloproteinase (MMP) inhibitor that can potentially impact PF4V1. Through the inhibition of MMPs, it may modulate pathways associated with extracellular matrix remodeling, indirectly affecting PF4V1 and its cellular functions. | ||||||