Peroxin 14 Activators
Peroxin 14 activators constitute a diverse set of chemicals primarily focused on influencing the peroxisomal activities. Pipecolic acid and phytanic acid, associated with lysine catabolism and peroxisomal metabolism respectively, can be indicators of peroxisomal activity, influencing PEX14. Additionally, the metabolism of very long-chain fatty acids (VLCFA), as well as specific fatty acids like DHA and EPA in peroxisomes, emphasizes the organelle's role in fatty acid breakdown. Accumulation of these fatty acids might indirectly indicate enhanced peroxisomal and consequently, PEX14 activity.
On another front, the role of PPARs in regulating peroxisomal proliferation brings forth a set of chemicals that act as PPAR ligands. Rosiglitazone and bezafibrate are PPAR agonists known to affect peroxisomal biogenesis. Alongside, fibrates, a class of drugs, showcase their potential to activate PPARs and in turn affect peroxisomes and PEX14. Natural ligands of PPARs, such as Prostaglandin J2 and 9-cis-Retinoic acid, also have a role in modulating peroxisomal functions and may influence PEX14 indirectly.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $94.00 $210.00 $1779.00 $8021.00 $16657.00 | 11 | |
A fatty acid metabolized in peroxisomes, potentially influencing PEX14 activity. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $104.00 $431.00 | ||
Another fatty acid metabolized in peroxisomes, which can have an effect on PEX14. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
A PPARγ agonist which can influence peroxisomal proliferation and thus indirectly influence PEX14. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $31.00 $46.00 $122.00 $204.00 | 5 | |
A pan-PPAR agonist, which can potentially induce peroxisomal biogenesis and affect PEX14 activity. | ||||||
PGJ2 (Prostaglandin J2) | 60203-57-8 | sc-201248 sc-201248A sc-201248B sc-201248C sc-201248D | 1 mg 10 mg 50 mg 100 mg 500 mg | $228.00 $1857.00 $9180.00 $13770.00 $64566.00 | ||
A natural ligand of PPARγ, which can modulate peroxisomal activity and consequently influence PEX14. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
Another natural ligand of PPARs, its presence can affect peroxisomal biogenesis and PEX14 indirectly. | ||||||