OTTMUSG00000010657 Activators
LOC666532, also known as Zfp991, is a gene with essential roles in cellular processes, particularly in gene expression regulation and DNA integrity maintenance. Its activation is crucial for maintaining proper cellular functions. The general mechanisms of activation of LOC666532 (Zfp991) involve the use of various chemicals that influence epigenetic modifications or induce DNA damage. These chemicals, such as 5-Azacytidine, Trichostatin A, Etoposide, 5-Fluorouracil (5-FU), Sodium Valproate, 3-Deazaneplanocin A (DZNep), Vorinostat, Doxorubicin, Valproic Acid, 5-Aza-2'-deoxycytidine (5-Aza-dC), Camptothecin, and Retinoic Acid, act on specific pathways and cellular processes that are associated with LOC666532 (Zfp991).
In summary, LOC666532 (Zfp991) plays a pivotal role in cellular processes, and its activation is achieved through the use of chemicals that influence epigenetic modifications or induce DNA damage. These chemicals are essential for maintaining the proper functioning of LOC666532 (Zfp991) and ensuring its role in gene expression regulation and DNA integrity maintenance.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine activates Zfp991 by inhibiting DNA methyltransferases, resulting in DNA demethylation and the reactivation of silenced genes, including the target gene. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A activates Zfp991 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target gene. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide activates Zfp991 by inducing DNA damage and DNA double-strand breaks, which trigger DNA repair mechanisms, resulting in the functional activation of the gene. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil activates Zfp991 through its incorporation into RNA and DNA, disrupting nucleic acid synthesis and leading to the induction of stress response pathways, ultimately activating the target gene. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Sodium Valproate activates Zfp991 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target gene. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid activates Zfp991 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target gene. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin activates Zfp991 by inducing DNA damage and DNA double-strand breaks, which trigger DNA repair mechanisms, resulting in the functional activation of the gene. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-dC activates Zfp991 by incorporating into DNA during replication, leading to DNA demethylation and the reactivation of silenced genes, including the expression of the target gene. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin activates Zfp991 by inhibiting topoisomerase I, causing DNA damage and single-strand breaks, which activate DNA repair pathways and ultimately lead to the functional activation of the gene. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid activates Zfp991 by binding to retinoic acid receptors (RARs) and forming a complex that regulates gene transcription, leading to the functional activation of the gene. | ||||||